Protein Info for DvMF_0701 in Desulfovibrio vulgaris Miyazaki F

Annotation: integral membrane sensor signal transduction histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 545 transmembrane" amino acids 70 to 91 (22 residues), see Phobius details amino acids 219 to 240 (22 residues), see Phobius details PF00512: HisKA" amino acids 306 to 372 (67 residues), 53.8 bits, see alignment E=1.7e-18 PF02518: HATPase_c" amino acids 415 to 523 (109 residues), 88.8 bits, see alignment E=3.3e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_0701)

Predicted SEED Role

"FIG00606278: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DK62 at UniProt or InterPro

Protein Sequence (545 amino acids)

>DvMF_0701 integral membrane sensor signal transduction histidine kinase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MNSQNDAGGDNLSAAAGATSVAGTTSETRTAGASGAAGAPPTSPAASDRGGKGCALGCPR
QFFRSIKGKIFILFAVTFISIGALAALNYWSLSTVSQRLLLGERYDDLLNNILEVRRYEK
NYLFYRDAGSLTESLAYLERIDALTAELADDMAVVAGQAELVRFRDLLARYGHSVRTLVQ
GGTANQEELRTLGKSLIDEADALRKQKRERAHKALERTLVLPLAFLAVFLLLMVLVIKLI
STGLLRPLDMVAATTGRVGRGDFSPIATGAEQLSEIASFIHAFNRMAHELAVNQEHLLQA
RKMAALGTFTAGIAHELNNPINNVLLSAEGLREDYGEAIDADGQEMIGDIMQQAERASDI
VRNLLDFSRTEHPTFVALHPADVIGATVNLLKNQVMLSGISLAVHVPADLPMVRGDLRSL
QQVFMNLLLNGIQATPRGGAVAVVAMGVPPGHVAFEVRDSGPGIPEEIREHIFEPFFSTK
EVGKGTGLGLAVTYALVHRHEGRIEVHGGEGRGAVFTVLLPVARPGGDRESGDMIDDTAF
EEGDA