Protein Info for DvMF_0641 in Desulfovibrio vulgaris Miyazaki F

Annotation: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00111: Fer2
  • amino acids 7 to 60 (54 residues), 35.1 bits, 2.6e-12
• PF01799: Fer2_2
  • amino acids 75 to 149 (75 residues), 92.7 bits, E=3e-30
• PF01315: Ald_Xan_dh_C
  • amino acids 193 to 308 (116 residues), 79.5 bits, E=5.8e-26
• PF02738: MoCoBD_1
  • amino acids 325 to 567 (243 residues), 249.3 bits, E=8e-78
• PF20256: MoCoBD_2
  • amino acids 599 to 842 (244 residues), 214 bits, E=8.4e-67

Best Hits

Swiss-Prot: 73% identical to MOP_DESGI: Aldehyde oxidoreductase (mop) from Desulfovibrio gigas

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_0641)

Predicted SEED Role

"Xanthine dehydrogenase iron-sulfur subunit (EC 1.17.1.4) / Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4)" in subsystem Purine Utilization (EC 1.17.1.4)

MetaCyc Pathways

• inosine 5'-phosphate degradation (4/4 steps found)
• purine nucleotides degradation II (aerobic) (9/11 steps found)
• adenosine nucleotides degradation II (4/5 steps found)
• guanosine nucleotides degradation III (3/4 steps found)
• ureide biosynthesis (5/7 steps found)
• adenosine nucleotides degradation I (5/8 steps found)
• guanosine nucleotides degradation I (2/4 steps found)
• guanosine nucleotides degradation II (2/4 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• superpathway of guanosine nucleotides degradation (plants) (2/6 steps found)
• purine nucleotides degradation I (plants) (6/12 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• superpathway of purines degradation in plants (7/18 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.17.1.4

Sequence Analysis Tools

See B8DK02 at UniProt or InterPro

Protein Sequence (905 amino acids)

>DvMF_0641 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MINKHFIVNGIPRNLVVDPEATLADVLREQLLLTGVKVGCGEGQCGACSVILDGKVVRSC
AYKMRRLPDGASVTTIEGVGSPDCLHPLQLAWTAHGGAQCGFCTPGFIVSARQLLEENKS
PSRDDVRDWFQKHRNVCRCTGYKPLVDAVMDAAKVLRGEMSADDLCFKIPADGRIWGSKY
PRPSAIAKVTGTCDYGADLGLKLPSDALHLALVQAEVSHAKILSIDTSEAMKMPGVHSVL
THKDVKGKNRITGLITFPSNKGDGWDRPILCDEKVFQYGDALAIVCADSEKHARAAAEKV
KVQLEELPAYMSAPAAMAEDAMEIHPGTPNVYFIQNIAKGADTRPIFDGADVVVEGDYYV
GRQPHLPIEPDVGFAYTDGEGRLVIHSKSIGLHLHLYMIAPGLGLEPEKIVMVQNPAGGT
FGYKFSPTMEALVGVAAMATGRPVHLRYNYRQQQNYTGKRSPFFFNVRYAADKTGKIKAM
ETDWTVDHGPYSEFGDLLTLRGAQFAGAGYGIANIRGQGRTVCTNHAWGSAFRGYGAPES
EFPSEVLMDELAEKLGMDPLELRYLNVYRKGDTNPTGQDPEVYSLPEMIDILRPKYKAAL
DAARAGSTAAVKKGVGVAVGVYGCGLDGPDTSECDAELNPDGTVTIYNCWEDHGQGADMG
TLGTAHEALRPLGIAPQNIRLVLNDTSKAPNSGPAGGSRSQYVTGNAVRVACENLVEAMR
KPGGFRTYQEMVDEKIATKHRGAWTAAGTHCDENAQGKPFTAYMYGVFMAEVAVEVATGK
TTVDKLTMVADIGKINNKLLVDGQLYGGLAQGIGLALSEDYEDLKKHATMAGAGVPYIKD
IPDNIELIYVETPRGDGPFGASGVGELPLTVPHAAIINGIYKACGVRIRHLPALPEKVLA
GLKGA