Protein Info for DvMF_0024 in Desulfovibrio vulgaris Miyazaki F

Annotation: histone deacetylase superfamily (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00850: Hist_deacetyl" amino acids 79 to 278 (200 residues), 205.5 bits, see alignment E=6e-65

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_0024)

Predicted SEED Role

"Deacetylases, including yeast histone deacetylase and acetoin utilization protein" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DN42 at UniProt or InterPro

Protein Sequence (439 amino acids)

>DvMF_0024 histone deacetylase superfamily (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLEAKNRLGIIFFPAFDWAISATHPEREERLLYTQDQLREEGLFDIAGITEYKPEIATRE
DVERVHFCIPGVESVCTKSHLISAGGAITAARLVMEKEEEKAFALVRPPGHHAMKVVHGN
RGFCNINIEAVMLEHIREHYGPLRVAIVDTDCHHGDGTQDIYWNDRDTLFISLHQDGRTL
YPGTGFPHELGGPNAMGRTLNIPLPPGTSDKGFLHVIDNLVLPVLEDFKPDLIINSAGQD
NHFSDPITNMNFSARGYAMLNRRLNPDIAVLEGGYAIQGALPYVNLGICLAMAGLDFDGV
REPEFDPAAIAQSDQVTAYIERLCDEMLKVWRKPPALPKQGERSGDWWVRTKDIYYDTDG
ISESQVESVLLCPDCSGTVKIETWSTVNPLSVGIEIPISACDRCAGIGRRLLEEAHLKGN
YRYVQCIDRKAKKYTRYGF