Protein Info for Shewana3_4051 in Shewanella sp. ANA-3

Annotation: oligopeptidase A (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 PF19310: TOP_N" amino acids 28 to 149 (122 residues), 95.6 bits, see alignment E=1.9e-31 PF01432: Peptidase_M3" amino acids 222 to 676 (455 residues), 531.1 bits, see alignment E=3.5e-163

Best Hits

Swiss-Prot: 65% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01414, oligopeptidase A [EC: 3.4.24.70] (inferred from 100% identity to shn:Shewana3_4051)

MetaCyc: 65% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L2J9 at UniProt or InterPro

Protein Sequence (679 amino acids)

>Shewana3_4051 oligopeptidase A (RefSeq) (Shewanella sp. ANA-3)
MSNPLLNGAKLPLFSQIKPEHIQVAVEQAIAQCRAKIDEVLQTPGPFTWDNLVAPLEQVD
DELSQIWSPVSHMNSVVSTDEWRAAHDACLPLLSEYGTYVGQHQGLYQAYKSLRASADFD
QLSQAQQMVIEHSLRDFELSGIGLDDGQKVRYGEIVKRLSELTSGFSNQLLDATQAWTKL
ITDEAELAGLPDSAKAAAKAMAEARELEGWLFTLDFPSYLPVMTYSENRSLREECYRAFV
TRASDQGPNAGEFDNGPLMDEILALRHELAQLLGFDSFAEKSLATKMAETPAQVMAFLNE
LALRSKDQAKAELADLKAFALEQYGVSEMASWDLSFYAEKLQQHKYEISQELLRPYFPED
KVLSGLFYTVSRLFGLKIVEQTEFDRWHKDVRFFDIFDETGEHRGSFYLDLYARTGKRGG
AWMDDCRVRRHTPTGLQKPVAYLTCNFNGPVDGKPALFTHDEVTTLFHEFGHGIHHMLTK
IDVAGVSGINGVPWDAVELPSQFMENWCWQEEALAEISGHYETGEPLPKAMLDKMLAAKN
FQSGMMMLRQLEFSLFDFRLHHEYDPAKGARIQETLDEVRRQVAVLIPPAFNRFQHGFAH
IFAGGYAAGYYSYKWAEVLSADAFSRFEEEGIFNPDTGRSFLHNILEMGGSAEPMDLFKQ
FMGREPSIDALLRHSGIAA