Protein Info for Shewana3_3926 in Shewanella sp. ANA-3
Annotation: coproporphyrinogen III oxidase (RefSeq)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00224, [EC: 1.3.1.-] (inferred from 99% identity to son:SO_4520)MetaCyc: 99% identical to menaquinone C8-methyltransferase (Shewanella oneidensis MR-1)
RXN-18515 [EC: 2.1.1.350]
Predicted SEED Role
"Oxygen-independent coproporphyrinogen III oxidase, putative"
MetaCyc Pathways
- 8-methylmenaquinone biosynthesis (1/1 steps found)
- 7,8-dimethylmenaquinone biosynthesis (1/5 steps found)
KEGG Metabolic Maps
- 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
- Biosynthesis of unsaturated fatty acids
- Fatty acid biosynthesis
- Fluorene degradation
- Fluorobenzoate degradation
- Isoflavonoid biosynthesis
- Phenylalanine metabolism
- Propanoate metabolism
- Tryptophan metabolism
- gamma-Hexachlorocyclohexane degradation
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.3.1.- or 2.1.1.350
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0L275 at UniProt or InterPro
Protein Sequence (445 amino acids)
>Shewana3_3926 coproporphyrinogen III oxidase (RefSeq) (Shewanella sp. ANA-3) MSSVIQTLNRAIATPYQANITVPNWMLSSMERVMQYYVDKNLRLDTLSADIMPAPVEGKK YMLYAHVPFCHTLCSYCTFHRFMFKEDKARAYFISLRKEMEMVKALGYDFESMYIGGGTT TVLEDELARTIEHAKTLFPSIKEVSCESDPQHLDSPGFKQLKGLVDRMSIGVQSFNDDIL KMTDRLEKFGTGQQTFDKIMAAKELFPIINVDLIFGFRGQTDEVIQHDLDMASRLDPRQI TTYPLMITHQTRKSVKGKLAAPQADMANQYRQILNRLNGQYNQLSAWAFGKANDEGFDEY VIDYDEYLGVGSGSFSFLNDTLYVNTFSLRKYQERIAAGKMGVEQQKNYSKKDVMQYRFL LGMFSGRLSRKYFRETFGVNLDTALFKEMTSMKLIGAIKNDPTDPDNLIITDNGKMMGLL MMKEFYAGMDNVRAQLRKPLKPCDM