Protein Info for Shewana3_3814 in Shewanella sp. ANA-3

Annotation: AMP-dependent synthetase and ligase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 PF00501: AMP-binding" amino acids 13 to 386 (374 residues), 230.5 bits, see alignment E=3.1e-72 PF23562: AMP-binding_C_3" amino acids 428 to 539 (112 residues), 40.3 bits, see alignment E=4e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_3814)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L1W3 at UniProt or InterPro

Protein Sequence (554 amino acids)

>Shewana3_3814 AMP-dependent synthetase and ligase (RefSeq) (Shewanella sp. ANA-3)
MDNAIKTPVEMLAHWANTRGDEIYLRQPIKGQYLDFTWNEVQEKVQQLAGALRHLGLEPG
DKIAVLSKNCAEWFITDLALMHGGYISVPIYPTANTDTIRYVLQHSGAKAIFLGKLDHWA
DQEAGVGGELLRLAMPYETMPAQYQWEQLLKMGNPLIEAPLPELDQTMTLIYTSGSTGQP
KGAIQTFASYGWTCQAVVRDLRTNGNDRLLSYLPLAHITERVAIEGSSFYSGSTVAFVES
LDSFVADVQRAKPTVFFSVPRLWSLFQKNIIDKIGVGKLNLLLKIPLISSLVKHKIHKGL
GLNHCRLLGSGSAPIPPSLIHWYHSIGLDICEAWGMTENCAYSIINYPFDVRKIGTVGKP
VQDCQIRQGEDGELLLKSPGLMTAYYLQPEATAAAFDPDGFFHTGDLCAIDADGCVTITG
RVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPVALVQLSEGATLQAREEV
RTSLKATLDSVNPHLESHEHVDAIVVVNEPWTIENDVLTPTLKIKRHVLEKAFSERVDGI
RGAQVRWEDELSAK