Protein Info for Shewana3_3661 in Shewanella sp. ANA-3

Annotation: TPR repeat-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 transmembrane" amino acids 40 to 59 (20 residues), see Phobius details PF14559: TPR_19" amino acids 272 to 326 (55 residues), 27.1 bits, see alignment 1.1e-09 PF13432: TPR_16" amino acids 300 to 353 (54 residues), 16.1 bits, see alignment 3.3e-06 amino acids 368 to 423 (56 residues), 17.6 bits, see alignment 1.2e-06

Best Hits

KEGG orthology group: K12284, MSHA biogenesis protein MshN (inferred from 100% identity to shn:Shewana3_3661)

Predicted SEED Role

"MSHA biogenesis protein MshN" in subsystem Mannose-sensitive hemagglutinin type 4 pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L1G1 at UniProt or InterPro

Protein Sequence (447 amino acids)

>Shewana3_3661 TPR repeat-containing protein (RefSeq) (Shewanella sp. ANA-3)
MSVINKMLQDLDKRQQGHSLSNVAVHQAQYLGRPNPSRKWLVISLVSLLVGGLSVYAFQA
SYGVKSVADNSVNPVASSQTQPDNASPQIDTSPLETETTKSTYTTIPTEPTAEMVQVSPS
STEVPAKDMSASAESAPSVAQSARLNAAQVEPTSEPRAEPVATNTSTDTSNNAALTQESA
QTQAESQQVAVKANQADVNANQSEVKIIQTDPKASEPVVPAATQASRQTSPQASSPASAQ
AQSTGQMAIREVKLSPSQLAQKQLVLAADAEKQGQLVKAMDYYAKALRLDPSLHESRKQL
AALHYGQGELAQAAEVLAQGRLLYPQEFEFALLLARVQHVMGETDSALASLAQIPDSHSL
ARQKWLAQTDLAQKQGQYPLVEQAYRKLLQQEPQQGKWWMGLAYALDSQQQFGPASQAYR
TALSYSGLSTQATAFIEQRLQQLGDSQ