Protein Info for Shewana3_3042 in Shewanella sp. ANA-3

Annotation: phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 PF13185: GAF_2" amino acids 16 to 152 (137 residues), 62.5 bits, see alignment E=1.5e-20 PF13492: GAF_3" amino acids 18 to 152 (135 residues), 38.6 bits, see alignment E=4.1e-13 PF01590: GAF" amino acids 18 to 152 (135 residues), 72 bits, see alignment E=2.3e-23 PF05524: PEP-utilisers_N" amino acids 171 to 292 (122 residues), 84.6 bits, see alignment E=1.8e-27 TIGR01417: phosphoenolpyruvate-protein phosphotransferase" amino acids 171 to 730 (560 residues), 424.9 bits, see alignment E=2.3e-131 PF00391: PEP-utilizers" amino acids 318 to 390 (73 residues), 71.8 bits, see alignment E=9.1e-24 PF02896: PEP-utilizers_C" amino acids 417 to 705 (289 residues), 319.5 bits, see alignment E=6.1e-99

Best Hits

KEGG orthology group: K08484, phosphotransferase system, enzyme I, PtsP [EC: 2.7.3.9] (inferred from 100% identity to shn:Shewana3_3042)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.9

Use Curated BLAST to search for 2.7.3.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZP8 at UniProt or InterPro

Protein Sequence (744 amino acids)

>Shewana3_3042 phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq) (Shewanella sp. ANA-3)
MLNTLRDITQAVASAHSLETALEVLVSSTKAAMETQCCSVYILDQQELVLSATDGLEKSA
VGRVRMPLTQGLVGLAAEREEAVNLADARLHPRFKLFPEVAEEEYRAFLAVPIIYQKAVV
GVIVVQQASARQFSEGEEAFLMTLAAQLAMAIRGLKQKAQVSSLHQQILFQGTSASSGIA
IAHALVLGGEISLEQPDVRCEDIVLESSRLVAAMGRCKEAIGALSQRFDREQDEEVASIF
NALQLLLDDVSLGGEYAREVQQGWEAESAVSRVSLRYIQQFLAMEDPYLKERASDIRDLG
QKVLRQLIEPERLELEPDKPVILVTREADATMLAEFPRQKLAGIVTELGGVNSHAAILAR
ALGVPAITGVEQLLSADIDQKLLVVNASRGQLMVSPSPAIVSEYRSLISAQKALQRQYAQ
ELALPSVMLDGTRIRLYLNAGLLSGVASEIAEGADGIGLYRTEIPFMLQQRFPSESEQVK
VYQQVLSAASGRPVVMRTLDVGGDKPLPYFPIKEDNPFLGWRGIRLSLDHPELFLVQLRA
MLQAGGECKQLSILLPMVSNLDEIDQSLAYLEQAYVELKNDVNSQIEMPRIGIMLEVPAL
LYQLDEVAKRVDFVSVGSNDLTQYLLAVDRNNPRVSSLFDSYHPGILRALHQARLDCDYH
ELDISICGELAGEPMGAILLVAMGYQHLSMNQGSLARINYLLRRVSRADLTQLLSQALSL
SNGFQVRELVKEYLTQQGLATILN