Protein Info for Shewana3_3018 in Shewanella sp. ANA-3

Annotation: signal recognition particle protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 TIGR00959: signal recognition particle protein" amino acids 2 to 430 (429 residues), 590.2 bits, see alignment E=1.2e-181 PF02881: SRP54_N" amino acids 5 to 82 (78 residues), 81.1 bits, see alignment E=1.4e-26 PF06414: Zeta_toxin" amino acids 97 to 194 (98 residues), 24.9 bits, see alignment E=3e-09 PF00448: SRP54" amino acids 100 to 296 (197 residues), 251.7 bits, see alignment E=1.1e-78 PF01656: CbiA" amino acids 110 to 257 (148 residues), 28.9 bits, see alignment E=2.5e-10 PF02978: SRP_SPB" amino acids 328 to 428 (101 residues), 120 bits, see alignment E=1.2e-38

Best Hits

Swiss-Prot: 78% identical to SRP54_ECOLI: Signal recognition particle protein (ffh) from Escherichia coli (strain K12)

KEGG orthology group: K03106, signal recognition particle subunit SRP54 (inferred from 99% identity to son:SO_1356)

Predicted SEED Role

"Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)" in subsystem Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZM4 at UniProt or InterPro

Protein Sequence (457 amino acids)

>Shewana3_3018 signal recognition particle protein (RefSeq) (Shewanella sp. ANA-3)
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAV
GQEVAKSLSPGQAFIKIVQSELEKSMGEANQALDLATQPPAVVMMAGLQGAGKTTSVAKL
GKLLRTRHKKSVLVVSADVYRPAAIKQLETLATEVDVEFFPSDVSQKPIDIAKAAIAHAK
LKFIDVVILDTAGRLHVDEAMMDEIKALHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDV
LSLIEEVERGVDKDKAMKLASKVKQGGSFDLEDFREQLQQMKNMGGMMSMIEKLPGVGQL
PPDALAQIQDGKMTRQMEAIINSMTAKERKNPDLIKGSRKRRIAAGSGTQIQDVNRLLKQ
FTQMQKMMKKMSAKGGIQKMMRGMRGMMPGGMKFPGR