Protein Info for Shewana3_2919 in Shewanella sp. ANA-3

Annotation: DNA helicase/exodeoxyribonuclease V, alpha subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 721 PF14490: HHH_4" amino acids 172 to 256 (85 residues), 50.7 bits, see alignment E=4.1e-17 PF13604: AAA_30" amino acids 343 to 517 (175 residues), 136.4 bits, see alignment E=3.1e-43 PF13245: AAA_19" amino acids 347 to 471 (125 residues), 105.3 bits, see alignment E=8.8e-34 PF01443: Viral_helicase1" amino acids 362 to 469 (108 residues), 26.7 bits, see alignment E=1.5e-09 amino acids 621 to 693 (73 residues), 26 bits, see alignment E=2.4e-09 PF13538: UvrD_C_2" amino acids 648 to 693 (46 residues), 39.5 bits, see alignment 1.3e-13

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 100% identity to shn:Shewana3_2919)

Predicted SEED Role

"RecD-like DNA helicase YrrC"

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZC6 at UniProt or InterPro

Protein Sequence (721 amino acids)

>Shewana3_2919 DNA helicase/exodeoxyribonuclease V, alpha subunit (RefSeq) (Shewanella sp. ANA-3)
MNTALHEDQMRVTSIPYRSTKMVIFSGVPLAKDSYKTNSGKYFVTIKADPDSIPVLPTLG
QHWSVKGARQIESVEMGDYVMQQHTYESPKHIECTLPETGEQLIRFIARESDFKGIGESK
ARALWQLLGKDFHATLKNDTPESRKRLTSILSEDSVEALFKGYAKYKNLAHCNWMSEHNI
PASVQQRLLKHHGEASIEVIKDNPYALMGFGLSFSAIEDIIKVTDFKSYVAKDDPRRLSA
ALEMAIRKEIEKGHTYTTHANVRPYLNNLLKDKTLVTQAFKSGHDKAQYILNPDTGAYHP
TAQLLMESVVAKRLNTLIKRNDLFDENANAAYCSAVAELPYELTPKQIEAVTTCLDNSVS
CITGGAGTGKTTVLRTALRAYHQLGFEIHAVALSGRAAMRLHESIGFVTSTIAKLLREAP
IEPCVEKTNHLLVIDEASMIDLPTMYRLVNHIHPSVRLIFTGDPDQLPPIGCGKVLADIV
EAKTVANTMLDIVKRQEGSTGIPEYSKLINQGVMPDRLSTGAIHFHETSKTDIAKVCCEL
YQQCPENSRVMAPTKALVSEINKLTQQAVNPDSTSLEFEINGDKFFLPLRMNDAVLFTQN
HYDKGIQNGSLGMLTNAKPSGDSYGEVTLDTGEKVEITQSVLDCMELGYAITLHKAQGSQ
FPRIIIALQNGRIVDRAWFYTAITRAESEIHIVGSSDDMKQITEAPSHSHKRNSYLKELL
S