Protein Info for Shewana3_2692 in Shewanella sp. ANA-3

Annotation: streptogramin A acetyl transferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF00132: Hexapep" amino acids 122 to 157 (36 residues), 34.7 bits, see alignment 5.1e-13

Best Hits

Swiss-Prot: 54% identical to VATA_STAAU: Virginiamycin A acetyltransferase (vat) from Staphylococcus aureus

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2692)

Predicted SEED Role

"Chloramphenicol acetyltransferase (EC 2.3.1.28)" (EC 2.3.1.28)

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.28

Use Curated BLAST to search for 2.3.1.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KYQ0 at UniProt or InterPro

Protein Sequence (224 amino acids)

>Shewana3_2692 streptogramin A acetyl transferase (RefSeq) (Shewanella sp. ANA-3)
MPTHSPSQLGPNPNDKSPLKGFPQVGFLKNFISRDNIIVGDYTYYDDPAGPERFESNVLY
HFDFIGDKLIIGKFCAIARDVKFIMNGANHQVSGFSTYPFYIFGNGWEKATPKPEDLPFK
GDTRIGHDVWIGYNATIMPGVNVGHGAIIASQAVVTKDVPPYAIVGGNPATVIKLRFDPE
VIDTLLAIAWWDWPIEKISEHLPAIVGADLSQLARLADGIHTRP