Protein Info for Shewana3_2629 in Shewanella sp. ANA-3

Annotation: DNA polymerase II (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 810 PF03104: DNA_pol_B_exo1" amino acids 189 to 309 (121 residues), 38.1 bits, see alignment E=1.6e-13 PF00136: DNA_pol_B" amino acids 401 to 783 (383 residues), 154.7 bits, see alignment E=5.6e-49

Best Hits

KEGG orthology group: K02336, DNA polymerase II [EC: 2.7.7.7] (inferred from 100% identity to shn:Shewana3_2629)

Predicted SEED Role

"DNA polymerase II (EC 2.7.7.7)" in subsystem DNA-replication or DNA Repair Base Excision (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KYI7 at UniProt or InterPro

Protein Sequence (810 amino acids)

>Shewana3_2629 DNA polymerase II (RefSeq) (Shewanella sp. ANA-3)
MNPPESLTHDTAAPVSVQGRVLTRHAITRGATLVLQYYLATVSGPVLVELPDSEYICFCH
QSDMAALQLQTPGLALRFVPLTLKSFKRQSVAAIYAPSSSVFRHLQRIATDAGIPLFEAD
IRPEQRFLIERFVALDVAFLGHFVGKAGIDGQLSVFSAIRAKAVAPQSAIKLRSISLDFE
CSFDGLLYSVALYGRDAQSQPYEKVIMVGEAQPDAAIYIEWVNDEAALIHRLITWFTEFD
PDVIIGWSVVTFDLALLYRRALLHRIPLRIGRGGALLEWKVENKFRPETLSLPGRVVLDG
IDWLKAAFYQFERFSLEFVAQALLGEGKAIHDVENRAQEIDSLFAENKQGLAHYNLTDSR
LVWDIFEHTQLWDFALARAELTGLELGRVGASVAAFNHLYLPHLHRAGFVAPAEPASQGI
ESPGGYVMDSVPGFYQHILVFDFKSLYPSIIRTFLIDPKGLIEGLDNEDGSALDEPETVP
GFLGARFNRHQPILPKLIQNLSEQREKAKREANAPLSQAIKIIMNSLYGVLGSQGCVFHD
AKLASSITMRGHQIMKQTRAWIEEMGYQVIYGDTDSTFVYLGPEPDLSDINALGKQIAAR
MNQQWQSKIAQEFQLESFLELQFERHYEQFFMPTLRGSEEGSKKRYVGAWRNNSGALEIT
FKGMEQVRSDWSPLARKVQAELYERMFNQRDISGYLADVIGELQAGKRDDELVFSKRMRR
NLDEYTAKSSPHVKVARQLCELTGKSSFGKRGAQIDYVITVNGPEPVSHRSSTIDYQYYI
DKQIGPIAEPVFSIMKLNYTSITSNQLLLI