Protein Info for Shewana3_2491 in Shewanella sp. ANA-3

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR01887: putative dipeptidase" amino acids 121 to 525 (405 residues), 223.8 bits, see alignment E=2.5e-70 PF01546: Peptidase_M20" amino acids 129 to 525 (397 residues), 67 bits, see alignment E=2.3e-22 PF07687: M20_dimer" amino acids 314 to 428 (115 residues), 23.8 bits, see alignment E=3.6e-09

Best Hits

KEGG orthology group: K01270, aminoacylhistidine dipeptidase [EC: 3.4.13.3] (inferred from 100% identity to shn:Shewana3_2491)

Predicted SEED Role

"Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.13.3

Use Curated BLAST to search for 3.4.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KY51 at UniProt or InterPro

Protein Sequence (533 amino acids)

>Shewana3_2491 hypothetical protein (RefSeq) (Shewanella sp. ANA-3)
MELPQFNYTSLCRRFSYSLLAAALWTSTQAAASPITLSQDALKVADYAVSTYDVQMVESL
AHLISFNTQAVEGQTPDTNPAFIGFKSSLKSLSQELGLDYADHGYVVLIGLDANAVDAQR
SQVEKLGIVTHGDVQPANPALWAKSPYVLDTESEPGKLIGRGTEDDKGAIVTAMYAMKAI
KDKQLKREKRIELLVYLAEESDWDPLKAFLAHYTPAQMNITIDAEYPVVTAEKGWSKIGF
TVPNLELTQEQGAATNIPILMAFSGGYFASQVPQQAEAQIHAITPSLFEQLQTSAVNQQG
MKYRFERTCEQAVCDLHIFADGKAAHSSTPEDGVNAVTHLAALLQPYTWPKTTAALTVAA
MNELVGLGIYAEQFGELAYKDDFMGALTLAPTVVAQTSKGTEVTINLRRPVGKTPELLSA
QAKDALNKWQAEHQVTLIDVESYWGEPMVMKDAPHQQTLLDVFAHFTGIASPKPVAIGGS
TNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELTAAK