Protein Info for Shewana3_2247 in Shewanella sp. ANA-3

Annotation: exodeoxyribonuclease V, alpha subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 701 TIGR01447: exodeoxyribonuclease V, alpha subunit" amino acids 32 to 698 (667 residues), 558.5 bits, see alignment E=9.4e-172 PF21185: RecD_N" amino acids 37 to 137 (101 residues), 36.9 bits, see alignment E=1.6e-12 PF13245: AAA_19" amino acids 199 to 365 (167 residues), 117 bits, see alignment E=3.3e-37 PF13604: AAA_30" amino acids 201 to 379 (179 residues), 83.9 bits, see alignment E=5.6e-27 PF00580: UvrD-helicase" amino acids 204 to 269 (66 residues), 23.4 bits, see alignment E=2.1e-08 PF05127: Helicase_RecD" amino acids 213 to 346 (134 residues), 33.4 bits, see alignment E=1.9e-11 PF01443: Viral_helicase1" amino acids 618 to 671 (54 residues), 24.9 bits, see alignment 7.6e-09 PF13538: UvrD_C_2" amino acids 623 to 670 (48 residues), 40.1 bits, see alignment 1.2e-13

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 100% identity to shn:Shewana3_2247)

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KXF7 at UniProt or InterPro

Protein Sequence (701 amino acids)

>Shewana3_2247 exodeoxyribonuclease V, alpha subunit (RefSeq) (Shewanella sp. ANA-3)
MNHSTELTPPKESTQWVEAGALRLKAPLAELLKYWEKERLITPLDRHFALEMARLHPNDA
QEPLFMLLCALLSQQLSAQHTCLVLEHIVPANPMAESVNHCQIRLSLPELIARLQNFEAV
GEPHSNKPLIFDGGRLYLERYHHFETEVANALTRLSSSQPANSNDKDSDAPLRRQLDYLF
PNAASSHAATTLEPHIDWQKVATATALGKKLAVITGGPGTGKTTTVTKLLLLQQLGSPKQ
IRLVAPTGKAAARLSESIKASKARLEQELKQAQATNEQVQSHETQALLAALKQVPEEAST
LHRLLGVIPNSAQFRHHQGNPLRLDLLIVDEASMVDLPMMYKLLTALPEQAGLILLGDQD
QLASVEAGAVLADICAGLKYESDQHSEWRMRYSQAQAEQLSKLTSFDLRAYIHREPKIGD
SLCMLTHSHRFKGDAGIGLLASAVNRSDLAGILTVWQRGLAELTWLEHSMALSQTQAKIS
EPANNSGLHALLTQACEQYAEYLRPLQISDPSSVPSAIEAIARFNQYRILCAMRSGDYGV
EGINQTVTKALSQAKLIHPQQEFYLGRPIIIQSNDYNLGLFNGDIGLILQDEDRPERLMA
HFIKADGKLLKVLPARLPSHETCYAMTVHKSQGSEFNRVALVLPPNPSLVQWQLLTKELV
YTAITRAKQHFSCLGTQQVFERASQQATQRASGLADRLWRD