Protein Info for Shewana3_2156 in Shewanella sp. ANA-3

Annotation: peptidase M2, peptidyl-dipeptidase A (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01401: Peptidase_M2" amino acids 45 to 619 (575 residues), 808.6 bits, see alignment E=1.7e-247

Best Hits

KEGG orthology group: K01283, peptidyl-dipeptidase A [EC: 3.4.15.1] (inferred from 100% identity to shn:Shewana3_2156)

Predicted SEED Role

"Peptidyl-dipeptidase A precursor (EC 3.4.15.1)" (EC 3.4.15.1)

Isozymes

Compare fitness of predicted isozymes for: 3.4.15.1

Use Curated BLAST to search for 3.4.15.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KX67 at UniProt or InterPro

Protein Sequence (619 amino acids)

>Shewana3_2156 peptidase M2, peptidyl-dipeptidase A (RefSeq) (Shewanella sp. ANA-3)
MAILLNRPTTLALTIALTLGVTACNDAQSKAETTAAPAATNAAPDKAQAIAFIQDAEAQM
AQLSIEANRAEWIYSNFITEDTAALSAAVGEKVSAASVKFATEAAKYANVELDPANARKL
NILRSALVLPAPLDPAKNAELAQISSELNGLYGKGKYCFADGKCMTQPELSSLMAESRDP
AKLLEAWKGWREIAKPMRPLFQREVELANEGAKDLGYANLSELWRSQYDMKPDEFSQELD
RLWGQVKPLYESLHCYVRGELNNEYGDAIAPKTGPIPAHLLGNMWAQQWGNVYDLVAPDD
ADPGYDVTELLEQKGYDEHKMVKQAESFFTSLGFAPLPDSFWSRSLFLQPKDRDVVCHAS
AWDLDNLDDIRIKMCIQKTAEDFTVIHHELGHNFYQRAYKQQPFLFKNSANDGFHEAIGD
TIALSITPSYLKQIGLLEDVPDASKDIGLLLKQALDKIAFLPFGLMIDQWRWKVFSGEIT
PAQYNQAWWELREKYQGVKAPTDRSEADFDPGAKYHVPGNVPYTRYFLAHILQFQFHKAL
CDTAGDKGPVHRCSIYGNQAAGEKLNKMLELGASQPWPVALKEVTGTKGMDAKAVLDYFA
PLKTWLDEQNTAANRQCGW