Protein Info for Shewana3_2075 in Shewanella sp. ANA-3
Updated annotation (from data): L-arabinose ABC transporter, permease component 1 AraW
Rationale: Specifically important for L-arabinose utilization; the gene name is from PMC2996990
Original annotation: inner-membrane translocator (RefSeq)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02057, simple sugar transport system permease protein (inferred from 100% identity to shn:Shewana3_2075)Predicted SEED Role
"Predicted L-arabinose ABC transport system, permease protein 1" in subsystem L-Arabinose utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0KWY6 at UniProt or InterPro
Protein Sequence (405 amino acids)
>Shewana3_2075 L-arabinose ABC transporter, permease component 1 AraW (Shewanella sp. ANA-3) MKSSAETLSSTRMSADLISPQMNASEAHSSERQPRMQESHKTMVQEKNARYQAGKSTSMG RYLWPLLALSILLLANLFIDSSFFNISYQDDRLYGSLIDILNRSAPVALLSIGMSLVIAT GGIDLSVGAVMAIAGAVCANLLLVPDISLVTVIAAGLIVGLLAGCINGGLVSFLGIQPIV ATLLLMVAGRGVAQLINQGQIITFQHPGFAAIGVGQFLGLPMPVWIVIGMLTFSQLLLRK TALGLFIEAVGCNAKASRYLGINDKSIKLFAYGIAGLCAALAGMISTADIQGSDANNAGL WLELDAVLAVVIGGAALTGGRFSLILSVVGALIIQTLATTIIVSGLPAKFNLLIKAIVIL TVLLLQSAKFRRQLSALFKSKRHADAKPAEKATSAKASAATGEKL