Protein Info for Shewana3_2021 in Shewanella sp. ANA-3

Annotation: metal dependent phosphohydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 TIGR00277: HDIG domain" amino acids 141 to 185 (45 residues), 29.4 bits, see alignment 2.9e-11 PF01966: HD" amino acids 145 to 254 (110 residues), 29.7 bits, see alignment E=7e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2021)

Predicted SEED Role

"MptB, dihydroneopterin 2’,3’-cyclic phosphate phosphodiesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KWT3 at UniProt or InterPro

Protein Sequence (287 amino acids)

>Shewana3_2021 metal dependent phosphohydrolase (RefSeq) (Shewanella sp. ANA-3)
MSKPIFVWMKSIKFSANLPTANCEFIASNNLVSAITSADIARNCKVAYGLAQIIASHDYH
GNTVVCTIKAIPTRCSEQQYSQMIGLVNELKESLVGRFLRLLSFVTIDELQPFTDFILNK
EDILKLFMSSEASFKHHHCYKGGLFEHSIEVAEMTYQNAKHLGHSDVECQIGLIAALFHD
IGKIYPALNMKNNKYCAGPHESYAFALLAKPLGELGTLNSRVFSMLSDLLAIKPYGHKAR
YAIEHVLKQADRTSAESNFAKTQFKTLPSHYYFTKVDGSVIYRLNSL