Protein Info for Shewana3_1913 in Shewanella sp. ANA-3

Annotation: arsenate reductase and related (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 134 TIGR01617: transcriptional regulator, Spx/MgsR family" amino acids 21 to 131 (111 residues), 96.1 bits, see alignment E=8.1e-32 PF03960: ArsC" amino acids 24 to 130 (107 residues), 86.8 bits, see alignment E=4.8e-29

Best Hits

Swiss-Prot: 43% identical to Y103_HAEIN: Uncharacterized protein HI_0103 (HI_0103) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1913)

Predicted SEED Role

"FIG138056: a glutathione-dependent thiol reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KWH5 at UniProt or InterPro

Protein Sequence (134 amino acids)

>Shewana3_1913 arsenate reductase and related (RefSeq) (Shewanella sp. ANA-3)
MPQCEQNQCVPTAPLDRSIILTLFGIKNCDTVRKARKWIETHQLSVNFHDFREDGLAEKD
LQHWCQIAGWETVFNKRSTSFRALSDADKADIDQAKAIQLMLTHPTLIKRPVLTVGEQVL
VGFNEAEYKKVFSL