Protein Info for Shewana3_1876 in Shewanella sp. ANA-3

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 616 PF22521: HypF_C_2" amino acids 462 to 604 (143 residues), 27.8 bits, see alignment E=1.1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1876)

Predicted SEED Role

"Protein hydE" in subsystem Hydrogenases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KWD8 at UniProt or InterPro

Protein Sequence (616 amino acids)

>Shewana3_1876 hypothetical protein (RefSeq) (Shewanella sp. ANA-3)
MKHIRFEFTCSRQVPLYAHLCNQYLNYDALNISIGCDSQQDFGSHTYFIEAQGEQAQLEQ
LAEAIAADFLISVWLVDSGIHAIEAPQGQRTLLTVPSTEGALNVQSVAAFCQQCYPRFGD
NQAAQFGQLDLACTCCHGEKRLTSAQKALTLSDLKAMAAQLISQGSLDLASEGVQLSLTP
FAHTTASRPQLLICNPNTLNAHFCLKDNQVLALSSIEKPLISVRPTQDNQKLPAPLYDIC
FGYSRVVLVLSEILRQKGIDWVYLEGAHQRPALAWVDGAWAQLGSHTAENAATQTIKQFS
APEPLREDIHFLGFKAKWQANKKTRSHQGLLTVQAIPSEAETAEYAASEEDHTIADAALF
AALLNGKFTTHKQAKNAAVIYLSHHHTGQIVTCDNKGDTSLFFALPELPDNGYEIFHCLD
SSPQKAVAQKFKSLFPEDYLKLLSLKLNGRRDNLQSLWAIAAVLIGLNPQEETQSQAYLS
DALLAAAMRYHGANAPRIDYPLTKGEAHRSLNWCKTLGTLLSFRVAGHSDPSQLAFAMQD
SLADYLANWLEHIDLNIGVHNIALAGNELANETLCKRISLRLGKNFPLLVNRSLDLEGDN
LAVGALYVKQRQLNSL