Protein Info for Shewana3_1859 in Shewanella sp. ANA-3

Annotation: helicase c2 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 674 PF00270: DEAD" amino acids 70 to 122 (53 residues), 27.6 bits, see alignment 3.4e-10 PF13307: Helicase_C_2" amino acids 497 to 656 (160 residues), 154.2 bits, see alignment E=5.3e-49

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 100% identity to shn:Shewana3_1859)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KWC1 at UniProt or InterPro

Protein Sequence (674 amino acids)

>Shewana3_1859 helicase c2 (RefSeq) (Shewanella sp. ANA-3)
MKGPCSPLNHTRRPAMRQAKLQQSNQQSRDAQRPMSRLASEVLRAFASDGVLAKHIQGFS
ARQSQVEMAQIISEAIASKGNALIEAGTGVGKTFAYLIPAILSGKQVIVSTGSKNLQEQL
FLKDLPALTSMLGIAPKLALLKGRNNYLCQHRLDKQMQEASHIEARLLDDLLKINQWAGM
SKDGDIGGLTSVAENSPALPLVVSTKETCLGQRCEFYDACFTRKARGRAMDAKIIVVNHH
LFFADSVLKDTGFAELLPDPDVVIFDEAHLLPDICVSYFGQQSSSRTIDDYLQKLLQIYQ
TELSDTGQIAQFCQRCLTKLSDWHNALFSSGESDWRLQLGNKSIALASWDLLAELTALQK
LLLVHVGRSELLDDIAVKLTELNHKLNQFFNCDNPQAAYSVEFGSRFVMLRMSPINIARE
CQQLFVANTSWIFTSATLQVNRSLDHFAQELGISDAKAHILDSPFDYPRQALFCVPRQLG
NVTNQQQALKQLVDVCVKAIEAAQGRTFILFTSHKMLEQTALALRTRTQYPLLVQGQAGK
QSLLTKFRQLGNAVLLGTSSFWEGVDVRGKLLSCVIIDKLPFVSPDEPLYRARADNISRQ
GGDPFTQVSLPQAIIALKQGVGRLIRDEKDCGVLILCDNRIVNRAYGQAFLNSLPPMSRT
RDLDQALQFLRKIP