Protein Info for Shewana3_1521 in Shewanella sp. ANA-3

Annotation: phosphotransferase domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 PF02811: PHP" amino acids 9 to 163 (155 residues), 49.3 bits, see alignment E=3.6e-17

Best Hits

Swiss-Prot: 50% identical to RNAAM_HAEIN: 5'-3' exoribonuclease (HI_1400) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K07053, (no description) (inferred from 100% identity to shn:Shewana3_1521)

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KVD6 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Shewana3_1521 phosphotransferase domain-containing protein (RefSeq) (Shewanella sp. ANA-3)
MNTQSILADLHSHTTASDGHLTPSELVARALEKGVQLFAITDHDTVAGLGEARAFNQAQA
EPLKLISGVEISTRWNSYDIHIVALNFDETHAELLGFLAHQRELREQRAEEIGHRLAKAG
IEGAYEGAKKLAAGAAISRGHYARWLADNGHAVDMPSVFKRYLARGKTGYVPNNWGDMAS
AIEVIHNAGGLAVLAHPSGYKLSAKWLKRLVREFKEAGGDAMEVVLGQQTVDDRANLVAL
SVQNQLLASIGSDFHFPSNWIELGKNLYQPQGIDWVWQSGSWVERP