Protein Info for Shewana3_1285 in Shewanella sp. ANA-3

Annotation: conjugal transfer ATPase TrbE (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 816 PF03135: CagE_TrbE_VirB" amino acids 297 to 388 (92 residues), 33.7 bits, see alignment E=5.8e-12 PF19044: P-loop_TraG" amino acids 571 to 726 (156 residues), 32.1 bits, see alignment E=7.9e-12

Best Hits

KEGG orthology group: K03199, type IV secretion system protein VirB4 (inferred from 100% identity to shn:Shewana3_1285)

Predicted SEED Role

"Conjugative transfer protein TrbE" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KUQ0 at UniProt or InterPro

Protein Sequence (816 amino acids)

>Shewana3_1285 conjugal transfer ATPase TrbE (RefSeq) (Shewanella sp. ANA-3)
MLNLAEYRQRPALLADWLPWAGLIAPGVVLNKDGSFQRTARFRGPDLDSATQGELIAASA
RLNNALRRLGSGWALFIEAERRPAAGYPHSDFPEPLSWLVDEERRAAFEESGHHFESGYH
LTMVFLPPEESRARAAKLLYENSPGDGVDWRGRLDAFVAETDRVFDLLDGVMPEIAWLDD
DDTLTGLHATVSTRRYRLGVPEVPFHIDALLADCALVGGLAPMLGDQHLRVVSVRGFPTS
TWPGILDDLNRLGFGYRWSTRFLCMDKAEAEKELGRLRRQWFAKRKNVVALLRETIFQQE
SPLVDTDASNKAADADAALQELGSDQVAFGYLTATVTVLDADPAVADEKLRMVERVIQGR
GFVTIPETLNAVDAWLSSIPGNAYANVRQPIFSTLNLAHMMPLSAVWAGPEKNDHLDGPP
LIVTRTDGATPFRLVTHIGDVGHTLVAGPTGMGKSVLLAILAMQFRRYFGSRIFAFDMGR
SMRATILGLGGEHYDLGADGGIAFQPLARIDSEGYRTWAAEWVEGRLLHEGVTVGPDEKA
AIWSALGSLAGAPVEQRTLTGLSVLLQSNALRQALSPYVLGGAHGKLLDADRDRLGMADV
QGFEMEELMHSPAAVQAVLRYLFARFDERFDGAPTLLILDEAWLFLDEPSFAARIRQWLK
TLRKKNVSVIFATQSLADIKDSTIAPAIIESCASRIFLPNPQATEPQIRTIYEGFGLNSR
QIEIVATAQPKRDYYYQSRLGNRLFDLDLGPLALAFAGASTPQDQRDIDRVLTQAGAPGF
TGAWLRHRGLDWAADLLPSSPAAASFLNSQPLEVSP