Protein Info for Shewana3_1227 in Shewanella sp. ANA-3

Annotation: type IV pilus biogenesis/stability protein PilW (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR02521: type IV pilus biogenesis/stability protein PilW" amino acids 11 to 248 (238 residues), 299.5 bits, see alignment E=8.5e-94 PF13181: TPR_8" amino acids 49 to 77 (29 residues), 15.3 bits, see alignment (E = 6.6e-06) amino acids 149 to 180 (32 residues), 15.8 bits, see alignment 4.4e-06 PF13374: TPR_10" amino acids 114 to 142 (29 residues), 21.2 bits, see alignment (E = 8e-08) amino acids 148 to 176 (29 residues), 15.2 bits, see alignment (E = 6.4e-06) PF13424: TPR_12" amino acids 115 to 177 (63 residues), 41.2 bits, see alignment E=5.3e-14 PF07719: TPR_2" amino acids 151 to 181 (31 residues), 23.9 bits, see alignment 1.1e-08 PF14559: TPR_19" amino acids 161 to 218 (58 residues), 26.6 bits, see alignment E=2.2e-09

Best Hits

KEGG orthology group: K02656, type IV pilus assembly protein PilF (inferred from 100% identity to shn:Shewana3_1227)

Predicted SEED Role

"Type IV pilus biogenesis protein PilF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KUJ3 at UniProt or InterPro

Protein Sequence (262 amino acids)

>Shewana3_1227 type IV pilus biogenesis/stability protein PilW (RefSeq) (Shewanella sp. ANA-3)
MKHGLSGLSLAIALSLLVTGCVTERTYSGTDIPVSERKLDKVAAARERMQLGLTYLNRGN
SEQAKYNLDKAVEYAPELEDVHVAMAYYYQTVGDLVRTEQAYQDAINTKDASGDSMNNFG
VFLCQQKRYDKAEKMFLAAIEMPKYTRTASSYENLGICSRDAGQTEKARQYFQMALKYDP
RRSVSLLELAELGVEKGDYVDAQNQLARYHQVAAQTPESLTLGIKIEQALNDDAAMKRFG
ILLLAKFPASPQAKQYRVNLHQ