Protein Info for Shewana3_1222 in Shewanella sp. ANA-3

Annotation: DoxX family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 147 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 61 to 82 (22 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details PF07681: DoxX" amino acids 17 to 103 (87 residues), 91.5 bits, see alignment E=4.3e-30 PF04173: DoxD" amino acids 66 to 146 (81 residues), 27.6 bits, see alignment E=2.7e-10

Best Hits

KEGG orthology group: None (inferred from 99% identity to shm:Shewmr7_1292)

Predicted SEED Role

"Membrane protein, distant similarity to thiosulphate:quinone oxidoreductase DoxD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KUI8 at UniProt or InterPro

Protein Sequence (147 amino acids)

>Shewana3_1222 DoxX family protein (RefSeq) (Shewanella sp. ANA-3)
MKALITKLLTSAPSFAPLALRIPIGIILMAHGSQKLFGWFGGYGLEGTGQWMASIGLTPG
YLMALMAGSSEFFGGLLIIIGLLTRPTALVLSFTMVVAIFSVHIGNGLFLSNNGYEFGLA
LLAATVSLAVSGAGKLSADNLLAARLK