Protein Info for Shewana3_1144 in Shewanella sp. ANA-3

Annotation: peptidase S41 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1093 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF26549: Tricorn_N" amino acids 31 to 288 (258 residues), 256.8 bits, see alignment E=8.3e-80 PF07676: PD40" amino acids 62 to 97 (36 residues), 16.2 bits, see alignment (E = 3.4e-06) amino acids 486 to 512 (27 residues), 21.8 bits, see alignment (E = 5.7e-08) PF26550: Tricorn_2nd" amino acids 317 to 656 (340 residues), 206.2 bits, see alignment E=2.4e-64 PF14684: Tricorn_C1" amino acids 688 to 746 (59 residues), 75 bits, see alignment 1.4e-24 PF14685: PDZ_Tricorn" amino acids 772 to 859 (88 residues), 54.2 bits, see alignment E=5.2e-18 PF17820: PDZ_6" amino acids 811 to 847 (37 residues), 29.5 bits, see alignment (E = 2e-10) PF03572: Peptidase_S41" amino acids 887 to 1042 (156 residues), 110 bits, see alignment E=3.8e-35

Best Hits

KEGG orthology group: K08676, tricorn protease [EC: 3.4.21.-] (inferred from 100% identity to shn:Shewana3_1144)

Predicted SEED Role

"Tricorn protease homolog (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KUB0 at UniProt or InterPro

Protein Sequence (1093 amino acids)

>Shewana3_1144 peptidase S41 (RefSeq) (Shewanella sp. ANA-3)
MKLRHSVACCMLALGTLSAAHAIAQPASNQGYYRAPALHDQTLVFTAEGDLWTQTLGQKA
ATRLTTLPAEELGAAISADGKWVAYVANYEGASEVYVIPVAGGVAKRVSFENSRVRLQGW
TAKGEVLYSTDSGFGPANNWMLRLVNPETLATTDLPLADAVEGVVDANNQYVYFTRFGLQ
VTGDNAKVYRGGAKGELWRFKLGGKDEAQLLSGQHQGSVRQPMLWQDRLYFISDSDGNDN
LWSMALDGSDAKQLTQYKDWQVRGARMDQGKVVFQQGADIHVFDIASAKDSLLDIELTSD
FAQRREHWVKDPMDFATSANLALAGDKVVITARSHVAIAGIDGSRLVQVALPGTYRVRNA
IMSQDGKSVYAISDMSGQQEIWQFPADGSSGAKQLTKDGHTLRMTLSLSNDGRYLAHDDN
DGNVWLLDLKKNSNQKIISNGEGLGPYADIRWSADSRFIALTKSEIGKQRPQIVLYSVDE
NKAQTLTSDKYESYSPTFSRDGQWLYFLSNRQFTATPSSPWGDRNMGPVFDKRSQIFAIA
LVKNAKFPFSKPTELTAKTAEKTDSKDKPTPVKIDWAGIGERLWQVPVDSGNYSQLTAID
GRLYVLDQAIGDDTEPSLMRIKFSEQRPKAEVFAEDVANYSVSADGSKLLLRKKSNEKSL
LIVDAGDKLGDTENAKVQTDQWQLAISPTLEWQQMFEDAWLMHRDSFFDKKMRGLDWQAT
KAKYQPLLDRLTDRNELNDIFMQMMGELDSLHSQVRGGDLPKDPDAAKGASLGARLQQTN
DGVKIAHIYRNDPELPSQASPLSRIEVDAKEGDMLLAINGTPVTNVADVTRLLRNQQDKQ
VLLELKRGGQNHKTVVMPVSTQVDSQLRYLDWVNHNAGVVTEASKGKIGYLHLYAMGGGD
IESFAREFYTNYDKDGLIIDVRRNRGGNIDSWIIEKLLRRAWAFWQPTHGTPNTNMQQTF
RGHLVVLTDELTYSDGETFSAGIKALGIAPLIGKQTAGAGVWLSGRNSLTDKGMARVAEY
PQYAMDGRWVLEGHGVTPDIEVDNLPFATFNGHDAQLETAISYLKDELIKQPIPALKAQP
MPAKGMAEDIKAK