Protein Info for Shewana3_0908 in Shewanella sp. ANA-3

Annotation: catalase domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 7 to 395 (389 residues), 607.1 bits, E=1.4e-186
• PF06628: Catalase-rel
  • amino acids 425 to 484 (60 residues), 75.7 bits, E=2.6e-25

Best Hits

Swiss-Prot: 57% identical to CATA_RHIME: Catalase A (katA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 100% identity to shn:Shewana3_0908)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Sequence Analysis Tools

See A0KTM6 at UniProt or InterPro

Protein Sequence (486 amino acids)

>Shewana3_0908 catalase domain-containing protein (RefSeq) (Shewanella sp. ANA-3)
MSQQYLTSQSGSPIADDQNSLSAGERGPLLLQDWHLIEKLAHFNRERIPERVVHAKGTGV
YGTFTLTKDLSEYTIADHFNGVGKQTETFVRFSTVGGEMGSADAERDPRGFGLRFYTARG
NHDIVGNNTPTFFLRDGIKFPDFIHTQKRNPLTNLKDPQAMWDFWSLNPEAMHQVTILMS
DRGIPANYRQMHGYGSHTFSFWNAKGERFWVKFHFKSQQGVVNLTNEQADKLKGIDPDSS
QRDMVVAVTDGNFPRWTVNVQIMPESDANTYHINPFDLTKVWPHGDYPLIEIGVLELNRL
PQNYFAEVEQVALAPSNLVPGVGASPDKMLQARLFAYADAQRYRIGANYNQLPVNCPHAT
KANHHQRAGAMAGTQCPYHGSQTGGDATANYGPNSTAGALVELANFAEPPLRLDGEAARY
SRYNQDDYTQAGNLYRIFSEAEKARLVETISGSLRQASLDVQQRMLAHFHKADADYGQRI
QTALGL