Protein Info for Sama_3624 in Shewanella amazonensis SB2B

Annotation: protease, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 938 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 914 to 933 (20 residues), see Phobius details PF05547: Peptidase_M6" amino acids 113 to 392 (280 residues), 337.7 bits, see alignment E=1.5e-104 TIGR03296: M6 family metalloprotease domain" amino acids 123 to 450 (328 residues), 249.7 bits, see alignment E=5.3e-78 PF20773: InhA-like_MAM" amino acids 434 to 593 (160 residues), 100.6 bits, see alignment E=2e-32 PF20774: InhA-like_VEG" amino acids 601 to 733 (133 residues), 87.3 bits, see alignment E=3.3e-28 PF00801: PKD" amino acids 754 to 812 (59 residues), 41.2 bits, see alignment 3.2e-14 amino acids 828 to 894 (67 residues), 52 bits, see alignment 1.3e-17 PF18911: PKD_4" amino acids 758 to 825 (68 residues), 45.9 bits, see alignment 1.2e-15 amino acids 837 to 902 (66 residues), 67.2 bits, see alignment 2.6e-22 TIGR03501: GlyGly-CTERM domain" amino acids 915 to 936 (22 residues), 16.7 bits, see alignment (E = 9.7e-07)

Best Hits

KEGG orthology group: K09607, immune inhibitor A [EC: 3.4.24.-] (inferred from 100% identity to saz:Sama_3624)

Predicted SEED Role

"Protease precursor"

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SBS0 at UniProt or InterPro

Protein Sequence (938 amino acids)

>Sama_3624 protease, putative (RefSeq) (Shewanella amazonensis SB2B)
MVKRFNTPKLCALGILLALAGGQALAAPAMGSPADSGVINKERVLYWLIKRGEIAEDASD
ETKAAAVAAFVARAKSSTPAMEQIKAQEQSLASKARYAQKLRSQYQQVDDADVTKTVKVL
GVLVDFPDLPYNNNRLTAGDTDMYYSSYPAIHYSQMLFSASGFTGPSNQTLISGFQYFQQ
ASGNTFFFTGAVRDWVRADNNAAYYGGNDPSNEDNDKAVPELVLEAVTKAVAGMSASELA
SYDVEDPYDINSNGNLNEPDGIIDHIMLFHSSIGEEAGGGVLGADAIWSHRFFIQSDPSA
YGKAIPGTNLRAYGYTVQPIDAAAGVCTHEFGHDLGLPDEYDYDPDGDGSPVGSWSLMSG
GSWTGTVAGSEPVGFSPYARSFLQREYKGKWVKEQEISLDSLNSAGTDFNLVEGVNANGV
NQLSLKVPSEPLPFKAPYAGDYQYYSNKGHKLNNAMSFNVTLPVVDSLTLKMRAHWDIEF
DFDYMQVQVDGTPIPGNHTKATSYYEAGRNVITGSSANIAGNEGPDHWVELTYDLSAYKG
MSKQISIVYKTDEFEGGYGIAIDNLSIVSGSETLYSDDAETSDKMMLAGFVRTTDTRPGN
DRRYLIQLRSQNGIDKGLASHGYSPGVVLWFENFDYSDNNTTEHPGYGLIGVVDADQNLI
GTRGTDVQIRDAAFSIRQQTAYAGDTNLGPVSLFDDSLDYSAPLKPQAGMILPELGLTME
VIQLAANNSTATVRLKKHDGSVPEPTDMNVSVGVTFSGATANFTSTVTGGDGNYSYFWDF
GNGASSTQANPSYTYGNTGTYDISLTVTDGKGVGVTVTQQLSVTVPVTASFSQSVSQLTV
SFTNSSSGGDGNLSYTWSFGDGQSSTAASPSHTYAAAGSYTVTLTVTDGKGVSSTRSASV
TVSAPAVTPSDGGSGGGSLGWLATLALVLAGMARRRQA