Protein Info for Sama_3619 in Shewanella amazonensis SB2B

Annotation: formate dehydrogenase accessory protein FdhD, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 PF02634: FdhD-NarQ" amino acids 38 to 270 (233 residues), 258.7 bits, see alignment E=3.1e-81

Best Hits

KEGG orthology group: K02379, FdhD protein (inferred from 100% identity to saz:Sama_3619)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SBR5 at UniProt or InterPro

Protein Sequence (282 amino acids)

>Sama_3619 formate dehydrogenase accessory protein FdhD, putative (RefSeq) (Shewanella amazonensis SB2B)
MTAAKPHTRFIKTSAEAPLTIAVTAVDETGAVLDKQIACERPLTLYLNWRPIVTLMTLGA
RPEALALGYMKNQGFIKDLAQLESVIVDWAVSSAAIITREQTDDLDKKLSEKTVTTGCGQ
GTVYGDLMAGLDDIKLPVPSLKQSTLYGLLRNINDYNETYKNAGAVHGCGLCEGEQIRSF
VEDVGRHNAVDTLAGEMWLKDEVGSDKIFYTTGRLTSEMVIKVAKMGIPVLLSRSGVTQM
GLELAQQLGITLIARAKGRHFLVYHGAETIDFDATPGKTGQG