Protein Info for Sama_3145 in Shewanella amazonensis SB2B

Annotation: mechanosensitive ion channel (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 289 to 310 (22 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 359 to 379 (21 residues), see Phobius details PF21088: MS_channel_1st" amino acids 340 to 376 (37 residues), 25.8 bits, see alignment 1.3e-09 PF00924: MS_channel_2nd" amino acids 377 to 443 (67 residues), 69.1 bits, see alignment E=4.4e-23 PF21082: MS_channel_3rd" amino acids 450 to 532 (83 residues), 60.9 bits, see alignment E=2e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_3145)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAE1 at UniProt or InterPro

Protein Sequence (544 amino acids)

>Sama_3145 mechanosensitive ion channel (RefSeq) (Shewanella amazonensis SB2B)
MLTSYSNRMLNMRLLIPFLLGMSLLVPTAALAVSDEFRSNVEQLEHTIAQDLKALSQAKG
ELVAISEYRINQKTAELRQLINAEIEAPNTDTAYLQTLVENQLSFIQQTQAYLGKDIQRL
KNALGSSNDAELLLALSNRERERDTNFKKELQTLDWGSKLGMDTQPRRTELKQALAERAD
RLASLVSYTQEQLKQAVDEARTAGKDVSAEQTARVSELKARLEQNSVSLSTVVGLLEELG
ADTTALKQVLFTVSGDITQDVLDIDLVGSLLGKWLSVAESQAIENGPRMLFKVFIFLLIL
FVASLVAKLVKSVVKKAVSNSKLKFSKLLQDFFVSLSAKGVYTLGLLIALSQLGFELGPL
LAGFGIAGVIIGFALQDTLSNFASGMMILIYRPYDVGDLISAAGVTGRVSHMSLVSTTIK
TLDNQRLIIPNNKIWGDTINNITAEHHRRVDMTFGISYADNVEHAEKILLDIVNSHPKVL
KDPGVTVRLHLLGESSVDFVVRPWVRPDDYWEVYWDVTKAVKQRFDAEGITIPFPQRDVH
FYRA