Protein Info for Sama_3126 in Shewanella amazonensis SB2B

Annotation: MATE efflux family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 48 to 73 (26 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 135 to 156 (22 residues), see Phobius details amino acids 168 to 188 (21 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details amino acids 248 to 267 (20 residues), see Phobius details amino acids 285 to 303 (19 residues), see Phobius details amino acids 324 to 346 (23 residues), see Phobius details amino acids 359 to 382 (24 residues), see Phobius details amino acids 391 to 412 (22 residues), see Phobius details amino acids 418 to 437 (20 residues), see Phobius details PF01554: MatE" amino acids 22 to 182 (161 residues), 99.3 bits, see alignment E=1.9e-32 amino acids 247 to 407 (161 residues), 75.9 bits, see alignment E=3.1e-25 TIGR00797: MATE efflux family protein" amino acids 24 to 416 (393 residues), 183.5 bits, see alignment E=3e-58 PF14667: Polysacc_synt_C" amino acids 141 to 223 (83 residues), 33.9 bits, see alignment E=3.4e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_3126)

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAC2 at UniProt or InterPro

Protein Sequence (455 amino acids)

>Sama_3126 MATE efflux family protein (RefSeq) (Shewanella amazonensis SB2B)
MKDRHGLLTAPIAGVLLKMTLPNMLGILTILGFSLVDTFFVSQLGTEALAAISFTFPVTL
VLSSIAVGIGAGVSTNLGRLIGSGHAPDAKVFLHDALLLTFAIVGTLASLGLMFIDPLFS
LLGANEQSLPLIHEYMLVWYLGSPLLVLLMVGNQGLRSTGDTKSPAKIMALAAIINLILD
PLLIFGLGPFPRLEIQGAAIASVISWVLAMSLSSYLLIVKRHMLALTEIAWPRLKDNWRK
LAHIAQPAALMNLMNPIANAVIMAMLARIDHGAVAAFGAGTRLESVLLIVVMALSSSLMP
FVAQNLGAGQHQRARDALMMSLRFVLLFQFLLYLPLLLLAGPIAGLFSDEPKVVEWLTFY
IIALPAAYGPLGVVIITATALNAFHRPLASLIINVCRLFLLMLPLCALGSFLYGVKGLMV
ALPVTNALMGIACYYLASRVTEPDTVPGAGEKARG