Protein Info for Sama_2996 in Shewanella amazonensis SB2B

Annotation: ABC transporter, ATP-binding protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 635 PF00005: ABC_tran" amino acids 17 to 178 (162 residues), 82.6 bits, see alignment E=8.4e-27 amino acids 330 to 459 (130 residues), 72 bits, see alignment E=1.7e-23 PF12848: ABC_tran_Xtn" amino acids 217 to 295 (79 residues), 99.2 bits, see alignment E=2.3e-32

Best Hits

Swiss-Prot: 56% identical to Y658_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_0658 (HI_0658) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06158, ATP-binding cassette, sub-family F, member 3 (inferred from 100% identity to saz:Sama_2996)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ATP-binding protein" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S9Z2 at UniProt or InterPro

Protein Sequence (635 amino acids)

>Sama_2996 ABC transporter, ATP-binding protein (RefSeq) (Shewanella amazonensis SB2B)
MITLSQAQLIRGSKVLLDEANLTIYPGHKVGLVGANGTGKSSLLALIMGKLSLDKGDIQV
PREWRIASVAQETPALEVSALEYVLDGDMEFRELEAALRKAETDNDGHAIADLHGKLDAI
GGYSIRARAGALLAGLGFSEEKQSVSVKSFSGGWRMRLNLAQALLCRSELLLLDEPTNHL
DLDTMFWLEDWIKSYPGTLVLISHDRDFIDAIVDEIVHVENQKLNFYKGNYSTFERTRAE
RMAQQQVAFERQQRERAHMQSFVDRFRYKASKAKQAQSRLKALEKMTELLPAKADSQFYM
EFREPASLPNPLVAMENVSVGYGETPILGKVHLNLVPGARIGLLGRNGAGKSTLIKLLAS
ELKPLTGKYEPNPGLTIGYFAQHQLEYLHMDDSPLMHLQRLAPSHREQELRDFLGGFGFN
GDMALSPVAPFSGGEKARLVLALLVWQSPNLLLLDEPTNHLDLEMRHALTLALQTFEGAM
VIVSHDRHLLRLTCNDYYLVDAGQVSSFEGDLEDYHQWLLDAAKAAAAKASDNDAERPAQ
DKKQQKRLEAELRQKLSPLRKQQTKLEDEQHKIASRLALIEERLADTSLYEAQNKAELTK
ILAERTTLGQQQEESEMAWLELQEQIDVIEQAAQL