Protein Info for Sama_2952 in Shewanella amazonensis SB2B

Annotation: sensory box histidine kinase/response regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1763 transmembrane" amino acids 15 to 37 (23 residues), see Phobius details amino acids 307 to 328 (22 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 405 to 507 (103 residues), 23.2 bits, see alignment 3.2e-09 amino acids 515 to 636 (122 residues), 58 bits, see alignment 5.2e-20 amino acids 638 to 767 (130 residues), 49.9 bits, see alignment 1.7e-17 amino acids 898 to 1020 (123 residues), 62.6 bits, see alignment 1.9e-21 PF13426: PAS_9" amino acids 407 to 506 (100 residues), 24.5 bits, see alignment 1.2e-08 amino acids 522 to 629 (108 residues), 40.9 bits, see alignment 9.3e-14 amino acids 914 to 1014 (101 residues), 28.7 bits, see alignment 5.8e-10 PF00989: PAS" amino acids 516 to 571 (56 residues), 33.4 bits, see alignment (E = 1.8e-11) amino acids 901 to 1007 (107 residues), 28.7 bits, see alignment 5.2e-10 PF08448: PAS_4" amino acids 518 to 630 (113 residues), 23.1 bits, see alignment 3.3e-08 PF08447: PAS_3" amino acids 668 to 753 (86 residues), 64.2 bits, see alignment 5e-21 amino acids 925 to 1006 (82 residues), 39.7 bits, see alignment 2.2e-13 PF00512: HisKA" amino acids 1036 to 1101 (66 residues), 79.8 bits, see alignment (E = 5.7e-26) PF02518: HATPase_c" amino acids 1148 to 1261 (114 residues), 98.5 bits, see alignment 1.5e-31 PF00072: Response_reg" amino acids 1281 to 1388 (108 residues), 91.2 bits, see alignment 2.2e-29 amino acids 1422 to 1531 (110 residues), 87.6 bits, see alignment 2.9e-28 PF01627: Hpt" amino acids 1588 to 1662 (75 residues), 40.2 bits, see alignment (E = 1.5e-13)

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2952)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S9U8 at UniProt or InterPro

Protein Sequence (1763 amino acids)

>Sama_2952 sensory box histidine kinase/response regulator (RefSeq) (Shewanella amazonensis SB2B)
MQENTEKLSTFRSRILFQIAVPLIIIMTGVSGVTGWLNYKAEEKAFFADLAEKADFAAKR
LEFELTLAQQDTQTLAFTLGHLDAKAQLQQAPFLYQLLTDRLARNDSFYGSAVAFVPGFT
PGQERFAPYVFRQDLTIATLDIGKEAYDYTNGEWDWWTEALKRPKGYWTAPYYDDGAGNI
QMITFSQPFGDEEPLGVVTTDLALSSLPIRLGIDPKKLLVLDARGTLIYHPDNNLTRNAT
ISDWLVKDVASEEAAKKVLEGEAQEVALKDLNGVQYLASIAKVSPLAWRVLVITPQTELV
ETFLKGFSSLTLSLLVLALILLVTSYYSAKRLTEPLEALETGIVDFSKGLIKRLQKPEGV
VREIATLSHKFNEMAEVLEEREQALLDSRGNRFATLIDGMSDKSFYCSMTPDGNIDQVSA
GVEKVLGISPEVLKRKYQRLFSSNAINEQNWQFMEMALRGEAVPPHQVEMAGADGSLRRL
DLFMQPLLDDEGQLISVEMLFNDVTEQFSAAAWSNAVLEAAPEAMLIVDESGQLVFSNSR
CQELFGYSGEEMLNLNIDALIPENERHGHQGKRQLFIEGGRDKVMANGKPLHALKCGGEQ
FPVQIGLSLLPADSRGQRQVAASIRDLTEQLAVERQIRESESRFRGLVSNIPGAVYRTRI
NGTWTMEYVSDNITELTGYPAWHFIESKKRSFGSLILDEDAERCDAIISGALAEQHAFEV
EYRIRHRDGSLRWVHEKGKASYDEDGNPVWFDGSLNDITESKLAQERIEQSREQLETITE
SVPSTVYQLVWRSERDRRFTFLSSAAMATLGFHRNEVLDNFELVAERIVEEDRGEIIQML
AGRHGMQWTKAFRYHFPSGELRWLEAGARGSKQQDALVWNGYLMDISGRKRMETELAQSE
AHFRALFDNAGIGIVNLDDRGIIKDCNGQFVSDLGISSDSLKRKQLADLMHPEDRALATG
LYQALAESEQGSISGEWRMLDGDGELMWMAVIASVLEEGDGGERSVVMSIANITRLKLLS
DELMAAKEDADAANQAKSDFLANMSHEIRTPMNAIIGMSQLCLQTELDRKQRNYVEKIER
ASKSLLGIINDILDFSKIEAGKLDIEVVPFQLDTILEDLGDMFSVKAADKQLELLFSVAP
GVPTHLEGDPLRLSQVLINLMNNAIKFTERGEVMLSISELARDEDQVQLKFAVRDSGIGL
TAEQQAKLFKSFSQADTSTTRKYGGTGLGLAICKQLVELMGGEIGVDSQFGNGSTFYFTV
SVKVAQNAQLNVEQELEGMAVLVVDDNSTARDILRTTLQSMGFSVDSARSGMEALEKCAE
RDYRIALIDWKMPEMDGTETAARMRELKQPPLILMVSAHANSEFIDKVEEMGINGYITKP
ISASRLLDGIMSALGRQGHKPVRRKAQPMDAQKLSGLKGKRILLVEDNEMNQEVASEFLE
QVGVVLSIADNGQIALEKLGQQSFDLVLMDCQMPVMDGYQATRELRKLPGLAELPVVAMT
ANAMAGDKEMCLLAGMNDHIAKPIEVGILYQTLLQYLCPEAKGLESADADAAADQEVTSL
TSWPEHEDLDIDRGLQLVQNSERLYRRILERFVTSQAQAGKKIRKALALGQQEDAVRLAH
TLKGVAGNLSADTLVEEARQLEAKLAQGEACEAELEAVETRLVTIVAAIERWMTEGVEEQ
GVESGEPLSADALKEVLNTLVTQLEDADADAVSTLESLSGQVVAGIWARLKPVSQMVAGY
QFDDGADLVRELIQELETDGESA