Protein Info for Sama_2928 in Shewanella amazonensis SB2B

Annotation: LysR family transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 transmembrane" amino acids 97 to 114 (18 residues), see Phobius details amino acids 227 to 245 (19 residues), see Phobius details PF00126: HTH_1" amino acids 3 to 64 (62 residues), 68.7 bits, see alignment E=3.5e-23 PF03466: LysR_substrate" amino acids 91 to 293 (203 residues), 143.5 bits, see alignment E=6.2e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2928)

Predicted SEED Role

"LysR family regulatory protein CidR" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S9S4 at UniProt or InterPro

Protein Sequence (296 amino acids)

>Sama_2928 LysR family transcriptional regulator (RefSeq) (Shewanella amazonensis SB2B)
MDLRAIRYFMEVVDAGGFAKASEKVHLTQPALSKAVRLLEESLELQLIERGKRGVHLRLT
PAGEVVYRHGLALLATRDDMLAELEAMRSLRGGRLKFGLAPLGSAELFAPVIARFRSLYP
KIDMQLLVRGGIEQTTALRKGEIELATGITALDSEFEGLRIRKDPMVVVLPRQHFLAHRR
ELALHELADTAHILFEPEYALHQLVVDACEQSGFSPIDVTRVSHPDFGIALVAAGTGAMI
LPSYIAERHMVAGVVSVPLKETDLHWELSLFWRRGQPLSFAAEAMIALVKERLGGL