Protein Info for Sama_2805 in Shewanella amazonensis SB2B

Annotation: HlyD family secretion protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 49 (22 residues), see Phobius details PF13533: Biotin_lipoyl_2" amino acids 63 to 110 (48 residues), 26.5 bits, see alignment 6.7e-10 PF16576: HlyD_D23" amino acids 210 to 303 (94 residues), 33 bits, see alignment E=5.9e-12 PF13437: HlyD_3" amino acids 223 to 309 (87 residues), 25.1 bits, see alignment E=3.7e-09

Best Hits

Swiss-Prot: 43% identical to YIBH_ECOLI: Inner membrane protein YibH (yibH) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2805)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S9F1 at UniProt or InterPro

Protein Sequence (381 amino acids)

>Sama_2805 HlyD family secretion protein (RefSeq) (Shewanella amazonensis SB2B)
MDLLLILTYAAICVVIFKVFKIPLNKWTVPTAVLGGIVLLGTLLLLMNYNHPYSRFAREY
FVTVPINPLVTGKVVEVAVMPNVPIREGEVLFRLDPRPFESALIQKQAALKAAEQEVPQL
EAAWETARASVERAQADRDRSKSEYERYEAGRRKGGANSPFTALELDNKRQLYFAAEAQL
TAARAEEMRVRYAYESNIDGVNTKVAAARAEVAKAEFDLEQSVVRAPTDGVVTHMALRPG
MVVVPMPLRPVMSFIPNEQRYFVGAFWQNSMLRLKAGDQAEVILDAAPGQVFKGRVARVL
PAMAEGEVQANGQLQSSARMFQRGRVLVMIEFDRSDEIQAFPAGVAGQVAIYTDHFSHVA
VMRKVLLRMQGWLNYLFGEGH