Protein Info for Sama_2511 in Shewanella amazonensis SB2B

Name: dnaK
Annotation: molecular chaperone DnaK (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 637 TIGR02350: chaperone protein DnaK" amino acids 3 to 600 (598 residues), 954.6 bits, see alignment E=9.1e-292 PF00012: HSP70" amino acids 4 to 599 (596 residues), 886.1 bits, see alignment E=9.8e-271 PF06723: MreB_Mbl" amino acids 116 to 375 (260 residues), 45.5 bits, see alignment E=4.7e-16

Best Hits

Swiss-Prot: 100% identical to DNAK_SHEAM: Chaperone protein DnaK (dnaK) from Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)

KEGG orthology group: K04043, molecular chaperone DnaK (inferred from 100% identity to saz:Sama_2511)

MetaCyc: 80% identical to chaperone protein DnaK (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S8K7 at UniProt or InterPro

Protein Sequence (637 amino acids)

>Sama_2511 molecular chaperone DnaK (RefSeq) (Shewanella amazonensis SB2B)
MGKIIGIDLGTTNSCVAVLDGGKARVIENAEGDRTTPSIIAFTEDETLVGQPAKRQAVTN
PTNTFFAIKRLIGRRFKDDEVQRDVNIMPFKIIQADNGDAWVESRGKKMAPPQVSAEVLK
KMKKTAEDFLGEEVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGI
DKKQGDNIVAVYDLGGGTFDISIIEIDNNDGDQTFEVLATNGDTHLGGEDFDNRLINYLA
DEFKKEQGLDLRNDPLAMQRLKEAAEKAKIELSSTNQTEVNLPYITADATGPKHLVVKVT
RAKLESLVEDLIQRSLEPLKVALADADLSVSDINEVILVGGQTRMPKVQEAVTNFFGKEP
RKDVNPDEAVAVGAAVQAGVLAGDVKDVLLLDVTPLSLGIETMGSVMTKLIEKNTTIPTK
ASQVFSTADDNQSAVTIHVLQGERKQASANKSLGQFNLEGIEPAPRGMPQIEVTFDIDAD
GILHVSAKDKKTGKEQKITIKASSGLSDEEVAQMVRDAEAHADEDKKFEELAQARNQADG
LVHATKKQVEEAGDALGSDDKAKIEAAIAEVEKAVKGNDKEAIDTATQSLIEASAKLVEI
AQAKAQGAQSSAQGSSAEKTADDVVDAEFEEVKDDKK