Protein Info for Sama_2406 in Shewanella amazonensis SB2B

Annotation: ATP-dependent protease, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 791 PF20437: LonC_helical" amino acids 89 to 122 (34 residues), 58.7 bits, see alignment (E = 9.2e-20) PF13654: AAA_32" amino acids 318 to 449 (132 residues), 171.2 bits, see alignment E=2.2e-54 PF20436: LonB_AAA-LID" amino acids 477 to 541 (65 residues), 80.1 bits, see alignment E=2e-26 PF05362: Lon_C" amino acids 651 to 753 (103 residues), 40.5 bits, see alignment E=4.8e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2406)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type II" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S8A4 at UniProt or InterPro

Protein Sequence (791 amino acids)

>Sama_2406 ATP-dependent protease, putative (RefSeq) (Shewanella amazonensis SB2B)
MAITTLATDKLYRVSTLAGLAPDCFSTATLPPLDDIIGQERAQSAVEFAMSIHEKGYNIY
AIGQNGLGKRTMMLRYLKRHHFDANQRFDWCYVANFDDNRVPRVLRLPAGKGNGFKKDIE
KLSLRLVKALPLAFDNEMYYSRADKLKTELSRQQEAALTALTEEAKNKSISLSLSVQGDY
QLMAMNGEEPHTEESYSALTDEEREVFENSIKGLEKRLRGIIRQLTEWEEEFSQKQQEHD
EQVAKEVLAHFFKPLKAKYRELDDIKAFLGEMQRDILDNLDIFLEESEEQLGLAYAALDK
KMPRRYQINVLVCQDEHKFPVVVEESPNYHSLFGYIENATFKGTVFTDFSLIRPGSLHKA
NGGVLLMDAIKVLERPYVWDGLKKALRSRSLDLNSLEREVTLSGTISLAPEPIPLDVKII
LFGDYQTYQLLQQYDPDFNELFRVTADFEDVMPRHDESEALYARFISSIVHDNNMLHCNR
SALARIIEYSSRQADDQTRLSLHSANIANLLRETNYCANNVGASEIGREHVEMALRNQEL
RVCRLKDMVMQQFHSGQTLFSAEGAVTGQVNALSVISTTDHEFGAPNRITATTAYGKGEV
LDIEHKVRLGGRIHSKGVWILTAYLSSLLGKQRPIPLTTFLTFEQSYSGVDGDSASMAEC
CAIVSAISGVPIRQDLAITGSMNQFGESQPIGGVNEKIEGFYDVCGIKGRTGTQGVIIPS
SNVKNLMLRSDIVDAAGRGEFHIYAVDHVTEAMALLTGLEVGNVDDASFDTLLGRAVSRL
TVLGKHKLDND