Protein Info for Sama_2301 in Shewanella amazonensis SB2B

Annotation: response regulator receiver protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 PF06490: FleQ" amino acids 7 to 111 (105 residues), 99.2 bits, see alignment E=4.4e-32 PF00158: Sigma54_activat" amino acids 133 to 300 (168 residues), 249 bits, see alignment E=5.1e-78 PF14532: Sigma54_activ_2" amino acids 134 to 304 (171 residues), 69.9 bits, see alignment E=6.7e-23 PF07728: AAA_5" amino acids 157 to 276 (120 residues), 30.3 bits, see alignment E=1e-10 PF02954: HTH_8" amino acids 431 to 471 (41 residues), 49.6 bits, see alignment 6.8e-17

Best Hits

KEGG orthology group: K10941, sigma-54 specific transcriptional regulator, flagellar regulatory protein A (inferred from 100% identity to saz:Sama_2301)

Predicted SEED Role

"Flagellar regulatory protein FleQ" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S800 at UniProt or InterPro

Protein Sequence (476 amino acids)

>Sama_2301 response regulator receiver protein (RefSeq) (Shewanella amazonensis SB2B)
MMQTDQRILLVGNQTERIGRLSCILEFLGEQLETLDPSGLEQAVKETRFRALIVDLESLP
LEQVKVFATKIPWQPILLLGATDDLSANLIGSVEEPFNYPQLTELLHFCQVFGQQRRPDV
PTSGNQTKLFRSLVGRSEGIVNVRHLISQVAPSDATVLVLGQSGTGKEVVARNIHYLSER
RDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIGDMPLA
MQVKLLRVLQERVFERVGGSKPIQANVRVVAATHRNLENMIENNEFREDLFYRLNVFPIE
MPSLSERCEDIPLLLQELVSRVFNEGRGKVRFTQRAIESLKEHDWSGNVRELSNLVERLT
ILYPGGLVDVNDLPVKYRHIDVPEYCVEVSEEMLERDALASIFNDDEPVEIPETRFPSEL
PPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMSKD