Protein Info for Sama_2273 in Shewanella amazonensis SB2B

Annotation: CheW domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 transmembrane" amino acids 216 to 236 (21 residues), see Phobius details PF01584: CheW" amino acids 214 to 347 (134 residues), 63.7 bits, see alignment E=7.3e-22

Best Hits

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 100% identity to saz:Sama_2273)

Predicted SEED Role

"CheW domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S7X2 at UniProt or InterPro

Protein Sequence (359 amino acids)

>Sama_2273 CheW domain-containing protein (RefSeq) (Shewanella amazonensis SB2B)
MSKSVDETVVDFFRLLLTEDAQVSDDTSLTKVHTQNAPVGDISVVVSTGVGNAFTDANAP
TQETLTGSAAGEMASAPSKSQPVKTELQIAKSESAQSPRIAPSRDPLDKASLEKLLAPVF
DVAKPLEHPAVEQPVVEQKAASVESPPVVAETVTKPKIAVRTKVQENVKAQVTLETEQDV
TPVAPVQTAPQTQTGATPPSITKDLREELDDEFQVLFFKVAGLTLAVPLVSLGGIVKVER
INHIFGRPDWFLGVQTHRESQLNLVDTCAWVMPEKYNEELAQNVNYQYLVLLEDSNWGLA
CESLVNSVRIKQSQVNWRTTAGKRPWLAGVVKEQMCGILNVRALIQMLNAGLGCQDPIS