Protein Info for Sama_2172 in Shewanella amazonensis SB2B

Annotation: von Willebrand factor type A domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 56 to 72 (17 residues), see Phobius details amino acids 297 to 315 (19 residues), see Phobius details PF01882: DUF58" amino acids 84 to 214 (131 residues), 25.4 bits, see alignment E=1.5e-09 PF00092: VWA" amino acids 84 to 276 (193 residues), 70.2 bits, see alignment E=5.5e-23 PF13519: VWA_2" amino acids 85 to 196 (112 residues), 58.2 bits, see alignment E=2.4e-19

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 100% identity to saz:Sama_2172)

Predicted SEED Role

"BatA (Bacteroides aerotolerance operon)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S7M1 at UniProt or InterPro

Protein Sequence (327 amino acids)

>Sama_2172 von Willebrand factor type A domain-containing protein (RefSeq) (Shewanella amazonensis SB2B)
MLTLAFPWLLLLLPLPLLIKPVQRQTRGGFLHLPGSADLVADVSKSTPKARDMLKWLMWT
ALVLAVARPQWLGDPIELPSKGRDLMVAVDLSGSMQIEDMVLDNKTVDRFTLVQHVVSDF
IERRVGDRIGLILFGDHAYLQSPMTQDRRSVAQYLREAQIGLVGKQTAIGESIALAVKRF
ENLEESNRVLVLLTDGTNNAGSISPDKAAAIAAERKVTIYTIGVGAEMMERRSFFGRDRV
NPSMDLDEEQLQRIANATQGKYFRARSSEDLAAIYQEIDKLEPVSRDTQSFRPKQELFFY
PLALALFLSLLAALREGGLFASGRNAP