Protein Info for Sama_1563 in Shewanella amazonensis SB2B

Name: cpdB
Annotation: bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 702 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details TIGR01390: 2',3'-cyclic-nucleotide 2'-phosphodiesterase" amino acids 51 to 702 (652 residues), 897.3 bits, see alignment E=2.8e-274 PF00149: Metallophos" amino acids 53 to 299 (247 residues), 42.7 bits, see alignment E=8.9e-15 PF02872: 5_nucleotid_C" amino acids 397 to 597 (201 residues), 49.5 bits, see alignment E=5.4e-17

Best Hits

KEGG orthology group: K01119, 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC: 3.1.4.16] (inferred from 100% identity to saz:Sama_1563)

Predicted SEED Role

"2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16)" in subsystem Purine conversions (EC 3.1.4.16)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.4.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S5W4 at UniProt or InterPro

Protein Sequence (702 amino acids)

>Sama_1563 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (RefSeq) (Shewanella amazonensis SB2B)
MERAHRGAPGVNISRDTDMNQKHLLAVTIAAALGVSACGSDNNDVEKEVLVDLRVMETTD
LHTNIMDFNYYSGKEDPTIGLARTASLIKAAAHEAPNHVLVDNGDLLQGSPMGDYMAKIG
IAEGAVHPAYKAMNLLGYSVGNIGNHEFNYGLDFLEKSLAGAEFPYINANVYCADDNGCW
KGIKKGEHLFTPYLIEEKEVIDQNGDKHVIKIGYIGFVPPQIMLWDKQNLTGKVEPADIL
ETAQKYVPEMKAKGADIIIAIPHSGIGSVENPGDPMAENATYALTRVEGINAIMFGHSHS
IFPDARYSDLPNTDVEKGLLNGVAAVMPGRWGDNLGVVDFKLARKDGKWAVLDVKTEARP
IYDGANKAPLVDADKDIHDAVELEHQGTLAFVDEPIGVAAADMYSFLTLVQDDPTVQIVS
DAQIANVKAKLPSSLAHLPVISASAPFKAGGRHGTTSDADQYVQVDKGALTFKNAADLYL
YPNTMVAVKATGAELKDWLECSANQFNQIDPNKSEPQFLINWAGHPTYNFDVLDGMTYKI
DVTQPSKFDRDCKVVNENANRIVDLAFKDSDGKVYSGEELLTKEFIVASNNYRAFGGKFA
GTGSDHVVLELPDTNREALAAYITAESKYNETTGKYDGMVNPTADYNWDFVTINSAVTLD
VRFETQDSGKADAFIEQNKQRPMTKVGKDELGYAVYRIDLTK