Protein Info for Sama_1477 in Shewanella amazonensis SB2B

Annotation: endonuclease/exonuclease/phosphatase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 947 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00932: LTD" amino acids 21 to 127 (107 residues), 64 bits, see alignment E=3.2e-21 PF03372: Exo_endo_phos" amino acids 468 to 774 (307 residues), 24.8 bits, see alignment E=3.5e-09 PF00801: PKD" amino acids 794 to 859 (66 residues), 48.5 bits, see alignment 1.3e-16 PF18911: PKD_4" amino acids 798 to 864 (67 residues), 60 bits, see alignment 3.7e-20

Best Hits

KEGG orthology group: K07004, (no description) (inferred from 99% identity to saz:Sama_1477)

Predicted SEED Role

"Extracellular deoxyribonuclease PA3909 (required for catabolism of external DNA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S5M8 at UniProt or InterPro

Protein Sequence (947 amino acids)

>Sama_1477 endonuclease/exonuclease/phosphatase (RefSeq) (Shewanella amazonensis SB2B)
MKTKASLVALALAGVSANVFAADNLVISEYVEGSSNNKAIELYNPTAAAVDLSQYQLKFY
FNGNSTAGSNIALSGILASGATFVVADNDASADILNRTQLASNASFFNGDDAIVLEHLGS
VIDSLGQIGVDPGSQWGSGLLSTADNTLRRDGANLVADTDPYDAVTLSNWIGFAQDDFSN
LGQFSSGPTDPTDPTDPTDPPAEGMVCGTSATAIHSIQGAGTTSPMVGQIVEVEAVVVSN
QEAGLKGLFLQMADAEQDSDVQTSEGVFLYTGNAPTGYLVGDRVRVKAKVVEYQGLTELT
NLTDKTLCATAQPLPTAAALSLPVNDVTELEAFEGMLVNFSQNLVVNEVYNLGRYGEIML
GGRRHVIGTQVAAPGADALAVTAANQRDSILLDDGLTSQNPDPVIYPAPGLSATNTVRVG
DTVTNLTAVMHYGFGVYRLMPLDTVNFVASNPRTDAPALDAGNLKVASFNVLNYFNGDGL
GGGFPTARGANTAVEFERQRAKIISAMKAIDADILGLMEIENDGFGSESAIADLVNGLNA
ATEAGRYGYIDPAVPAIGTDAISVGIIYRTDKVTPEGAAAILDSSNSAVDEDGKVLFNDQ
KNRPMLAQAFRHLETDEPVVVAVNHFKSKGSDCVAENDPDLGDGQGNCNLTRTRAAKAVG
EFLNTEFADAPVLVIGDLNSYAMENPLTALNEAGLTELFAHLGKESAYSYVFSGESGQLD
HALANVALLEKVVDVTEWHINTDEPRILDYNVEFKSAGQVESLYSMDAYRSSDHDPVVIS
LELERANELPVANFSYQVRGRKVAFVANATDADGGINAIHWNFGDGTEAMGDAVEHKFAN
RGVYQVSLTVTDNLGGSTTVTQQVGVGVNADNKAPVAAIEHLDFGLFHLFVSASYDTDGR
IRKQLWQFNDGARFASSVVLRRAGSASEVNLTVTDNDGATDSTSLRF