Protein Info for Sama_1189 in Shewanella amazonensis SB2B

Annotation: phosphoglucomutase/phosphomannomutase family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 45 to 184 (140 residues), 135.9 bits, E=1.6e-43
• PF02879: PGM_PMM_II
  • amino acids 231 to 318 (88 residues), 76.9 bits, E=3.1e-25
• PF02880: PGM_PMM_III
  • amino acids 331 to 449 (119 residues), 52.2 bits, E=1.3e-17
• PF00408: PGM_PMM_IV
  • amino acids 530 to 550 (21 residues), 24 bits, see alignment (E = 6.6e-09)

Best Hits

KEGG orthology group: K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 100% identity to saz:Sama_1189)

Predicted SEED Role

"Phosphomannomutase (EC 5.4.2.8)" in subsystem Alginate metabolism or Mannose Metabolism (EC 5.4.2.8)

MetaCyc Pathways

• GDP-mannose biosynthesis (3/4 steps found)
• colanic acid building blocks biosynthesis (7/11 steps found)
• β-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation (1/3 steps found)
• β-(1,4)-mannan degradation (1/7 steps found)
• superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis (5/14 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.8

Sequence Analysis Tools

See A1S4U0 at UniProt or InterPro

Protein Sequence (585 amino acids)

>Sama_1189 phosphoglucomutase/phosphomannomutase family protein (RefSeq) (Shewanella amazonensis SB2B)
MDTQLAFKVKHWLARDPDAKSRAALEALVAAGDDRALEAAFDGRLAFGTAGIRGIVGPGP
MGMNRLLVRETSAGLGAYLEAQIKDAKRRGLVIGFDGRHDSRVFAHDAACVLSAMGFKVR
LTSHVAPTPLVAFGVKHFEAAAGIVVTASHNPPKYNGYKVYWENGAQIIPPHDAGIAACI
DRAANLELPWMPEPEAVKQGRLSFLQDDFFERYRRAILHSPLLHPAGESQAGRASLGIAY
TAMHGVGAPMAERVLRDAGFSQVYSVAAQREPDGNFPTVNFPNPEEPGAMDMVIAEAGDK
GALLACANDPDADRFALAARQSDGGYRMLSGDQTGALLCDYLLSHWQGAGVPLVGNTIVS
SALLHAIAAHYGAHSYTTLTGFKWLMNTAQQLETPQQPFLFAYEEALGYTVGNLVWDKDG
ISAQLCFANLAAELLAEGKDVWAALERLYRRHGLYVNRQVSIALGEGTPDIGAWLRDNPP
TEIDKRPVVAREDLKRLRKVYADGREEEIALPASDVLIYHLGASDATPGSTARVIVRPSG
TEPKIKCYYELVLPMADDIAMADAQLQGDALMTALVDGHQAGLPR