Protein Info for Sama_1158 in Shewanella amazonensis SB2B

Annotation: GGDEF family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 138 to 294 (157 residues), 143.5 bits, see alignment E=2.5e-46 PF00990: GGDEF" amino acids 140 to 291 (152 residues), 140.1 bits, see alignment E=2.9e-45

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_1158)

Predicted SEED Role

"diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S4Q9 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Sama_1158 GGDEF family protein (RefSeq) (Shewanella amazonensis SB2B)
MDFGIAAQVYPDDYHFGRSATVVDIHDGPDQLALINIVQQLHASLDPRTVFACFGKVLGQ
YLPLAGIQAQFAEMQLSWGKRIGVSLKRHLNNEICRSAVLDYRLDAPLTPAQIRVLQTLE
SMLVQPLLNAIQYQKMSEQAMFDTLTGLGNRNFYGQAIKHAVARASRHQDKLSLIVLDLD
NFKQLNDTHGHQFGDAVLRQFGALIKSAIRNTDQAFRIGGDEFVVLVRGELDSATLLCER
ILSKLAKGSFFYRNRIHTSLGAAEIQAGENQDNLYERADKALYQAKAAGRNCYRLSLQHP
VKG