Protein Info for Sama_0993 in Shewanella amazonensis SB2B

Annotation: ligand-binding sensor domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1250 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 798 to 818 (21 residues), see Phobius details PF07494: Reg_prop" amino acids 35 to 57 (23 residues), 15.2 bits, see alignment (E = 5.1e-06) amino acids 205 to 227 (23 residues), 15.5 bits, see alignment (E = 3.8e-06) amino acids 368 to 389 (22 residues), 19.5 bits, see alignment (E = 2e-07) amino acids 418 to 438 (21 residues), 15.8 bits, see alignment (E = 3.2e-06) amino acids 510 to 532 (23 residues), 17.4 bits, see alignment (E = 9.4e-07) PF07495: Y_Y_Y" amino acids 734 to 790 (57 residues), 43.6 bits, see alignment 5.6e-15 PF08447: PAS_3" amino acids 867 to 946 (80 residues), 48.7 bits, see alignment 1.9e-16 PF02518: HATPase_c" amino acids 1137 to 1242 (106 residues), 76.4 bits, see alignment E=6.2e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_0993)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S494 at UniProt or InterPro

Protein Sequence (1250 amino acids)

>Sama_0993 ligand-binding sensor domain-containing protein (RefSeq) (Shewanella amazonensis SB2B)
MKLILSSLILLCCSLLCAGAYGYKPAFQTLEAEHGLSMNTVNDLVTDSRGYLWIATQAGL
NRYDGKHFKIYTQSDAPNGPSANDISFLHLSAKGELWLLTENAGVNLYQPLTDTFKVFGA
EAGIPNVRFTGISEDASGALWLATDKLGVLEFSPSAGRVVKTHRIAGSGNVLGITADGRG
GFWLAMLGGVSHLTQDGQSRSPDKLRGLSVSAMTIDPAGNLWLGTDNMELLRYGQDDDSL
EDFSNLFPSDITRVAIADLLLDVYSHTNHHHNAISSNTIPATDNQGHLWISTSGAGLAEL
DIGKRRLERYEHSPADYRSLSNQTLTRLWLDEEQQLWIGTRSAGIARLSLPSRQLRHIHG
QSFEKDNLQNSDIRSFFRDSQGQLWVGSTGGLLRAKESAEGEIIGFLPHGLPLPELTQAF
ISFIREDDDGQLWIGTRGLGLVIVSKDRQSFRQFRHDPGNSTSLPSNTLYSLFRDAQRQF
WITTLDGGVARMDVNSGQFSAIDRSNSNLLPEDQVTGMAQSSDGTLWIATYGGGLAMLNT
QGQYRHFNTDSTPALPSNHLFSIFMEDNGKLWLASDNGVISLDTQTMAVDRIDKSKGLIG
DVVYLMILDAHHRLWAGTASGLSVIDTRTGKVRSFTREDGLQDNEFNFGAAFLDRDNSLY
IGGINGFNHIHPEDLPRRAPPRAPSIQSLMLMNQPADLPQSAKGKGEPGTLKINHTDTLF
ALGYQSAALTDAHQLSYEYRMLGLDDNWFTDNDLQQATFTGLSPGLYQFEVRARNIDGAQ
SPITAMGITIEAAPWQTWWAYGLYLLIATCILGLLLYMKLSKYRAKMALMDKIAVSEQRL
QQALSSSGDEFWDWEIAAQRLTRSNTYLSYPPQELNLANTLLVVIHPDDVAKVRAAMDDC
LYRGVDEFEVSYRGRTGEDQWLWVLNHGKVISRDETGRPERIMGTVKNIQRLKEAEEALR
ELNAELEQRVTVRTQELQDKNEELNTLLEELRQTRDELLDKEKMATLGGLVASITHEVNT
PIGISVTAASHLQDRVREFTAAFEKGEVDEDDFVLYQSEVNDCCKLMLTNLERAAKLISS
FKKVSVDQSHEELREFDLSQYVDEIFLSLNPLLSRTPHKYSYECDPQLLVNSNPGIFYQI
ISNLFNNSIIHAYPDGRSGTLRLTIKRTPEGIVLDYRDDGCGMSQEIQDNIFTPFFTTKR
GKGGSGLGMNIVYNLVHQVLEGDIELITAPHQGAHFIIRLPKSMELHRPQ