Protein Info for Sama_0821 in Shewanella amazonensis SB2B

Annotation: peptidyl-prolyl cis-trans isomerase FkbP (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 PF00254: FKBP_C" amino acids 15 to 105 (91 residues), 116.5 bits, see alignment E=2.9e-38

Best Hits

Swiss-Prot: 57% identical to FKBP_NEIMA: FK506-binding protein (fbp) from Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

KEGG orthology group: K01802, peptidylprolyl isomerase [EC: 5.2.1.8] (inferred from 100% identity to saz:Sama_0821)

Predicted SEED Role

"FKBP-type peptidyl-prolyl cis-trans isomerase"

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S3S2 at UniProt or InterPro

Protein Sequence (112 amino acids)

>Sama_0821 peptidyl-prolyl cis-trans isomerase FkbP (RefSeq) (Shewanella amazonensis SB2B)
MSELQIEDVIEGEGKAAVKGALITTHYRGWLADGTQFDSSHDRGQAFQCVIGTGRVIKGW
DQGIIGMKVGGKRRLQVPAHLAYGERQIGNMIPPNSDLTFEIELLEVLTRDD