Protein Info for Sama_0765 in Shewanella amazonensis SB2B

Annotation: cobyric acid synthase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 PF13500: AAA_26" amino acids 5 to 236 (232 residues), 66.3 bits, see alignment E=5.2e-22 TIGR00313: cobyric acid synthase CobQ" amino acids 6 to 496 (491 residues), 483.7 bits, see alignment E=3.2e-149 PF01656: CbiA" amino acids 6 to 236 (231 residues), 90.1 bits, see alignment E=1.7e-29 PF07685: GATase_3" amino acids 259 to 453 (195 residues), 170.9 bits, see alignment E=4.1e-54

Best Hits

Swiss-Prot: 100% identical to COBQ_SHEAM: Cobyric acid synthase (cobQ) from Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)

KEGG orthology group: K02232, adenosylcobyric acid synthase [EC: 6.3.5.10] (inferred from 100% identity to saz:Sama_0765)

Predicted SEED Role

"Cobyric acid synthase (EC 6.3.5.10)" (EC 6.3.5.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.5.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S3L6 at UniProt or InterPro

Protein Sequence (502 amino acids)

>Sama_0765 cobyric acid synthase (RefSeq) (Shewanella amazonensis SB2B)
MGFSTLMIQGTASDAGKTTLVAGLCRLLARQGLKVAPFKPQNMALNSAVTEDGGEIGRAQ
ALQAAACGLKPHTDFNPILLKPGSDTRAQVIVHGKALTSLEASAFFGPEGKGYKAIAIEA
VLESYNRLKQSFDYLLVEGAGSPAEINLRENDIANMGFAEAVDCPVILVADIDKGGVFAQ
LVGTLALLSESEQARIKGFVINRFRGDINLLQPGLDWLEAHTGKPVLGVVPYLHNLLLDA
EDALVPYQQAGADSGARFRVRVLVYPRTSNHTDFDPLRLHPGVDFDYLDIQHASPDALQG
ADLVILPGSKNVRADLECLKTKGFDCALRKHVRYGGKLVGICGGYQMLGIEIDDPDGVED
TPGSSDALEFLPLITELEGSKVLANVSGELSLGEEAVAVKGYEIHCGRTTVLGQLSRPLF
LVDDTGNPASDRGCISDDGAIFGCYLHGIFDTPAALDAVLAWAGYRGAARGTSLEEHREQ
QLERLADTLAEHLDMARLNSLF