Protein Info for Sama_0438 in Shewanella amazonensis SB2B

Annotation: signal transduction histidine kinase-like protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 755 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 504 to 522 (19 residues), see Phobius details PF17874: TPR_MalT" amino acids 74 to 245 (172 residues), 35.4 bits, see alignment E=4.1e-12 PF13374: TPR_10" amino acids 105 to 135 (31 residues), 15.2 bits, see alignment (E = 1e-05) amino acids 223 to 257 (35 residues), 25.1 bits, see alignment (E = 7.6e-09) amino acids 343 to 374 (32 residues), 16.9 bits, see alignment (E = 2.8e-06) PF13176: TPR_7" amino acids 151 to 180 (30 residues), 17.4 bits, see alignment (E = 2e-06) PF13181: TPR_8" amino acids 151 to 174 (24 residues), 13.5 bits, see alignment (E = 3.8e-05) amino acids 224 to 256 (33 residues), 12.2 bits, see alignment (E = 9.9e-05) PF13424: TPR_12" amino acids 151 to 214 (64 residues), 45.7 bits, see alignment E=3.4e-15 amino acids 223 to 295 (73 residues), 54.3 bits, see alignment E=7e-18 amino acids 303 to 374 (72 residues), 35.2 bits, see alignment E=6.5e-12 PF00512: HisKA" amino acids 540 to 597 (58 residues), 32.1 bits, see alignment 5.5e-11 PF02518: HATPase_c" amino acids 650 to 754 (105 residues), 84 bits, see alignment E=5.7e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_0438)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S2P2 at UniProt or InterPro

Protein Sequence (755 amino acids)

>Sama_0438 signal transduction histidine kinase-like protein (RefSeq) (Shewanella amazonensis SB2B)
MTQSSAVPHPEGRRSRLGGMPWLSALSSCVPAMMLAMMMALFLSGCGENQAGAAASTEIS
GDARVQELLTLAAASRNDDPHKTIDYSSQALTLLKEIPEPASEVMALSNLAWAKMLLGDF
TEAAQYGEAALTLAENQHQPEMLVVPLNVTGLIYWRQSQLDKALTYYQRALEVAKGLNKR
SFEATTYNNMGLIHSDKAEYQLALECFTRARDIHQGLGDERPLATALNNIAGIHATLGDY
GEALANQQASLRIREKLDDKPGVAELHHNMGITYEQIGDLKESMLQLQQGLRGFEALGDK
TGMAQALTALGMVNQKLKNDVDARISMEQALAYGEELNDGNITATALMSLGKLALAMGDA
QGARRYLERGLAIADRLGLVALQAQGRLRLADYFLVTSEVDVARERALQAQQLALTSGDR
SLLRDTYEILSQIYERKGDYQQALASHKEFKSINDALFNASSQDRLAWLRSSFEAEKRQR
QITELESEKALQAEVIKQQRVARNLWILALIAVAAIMLLLYGRHSQARVNQALQRSIQMQ
RDLMQAVAHEFRAPLARVQLAFDMLMEADAKEQPQLEDRVLRGLEELDELIREIVKLIKA
EGSPRRAPSESLSLAPLLQTLVARQHQLFPEKHLELAAIDEDLRLTASKKHLEWAINNLL
SNALRYSREQVRVSCQRESEHLCIIVDDDGPGVPASERERIFEPFVRLDPSRTRATGGIG
LGLAIARRLAENAHGHIRVGDSPLGGARFELIWPY