Protein Info for Sama_0250 in Shewanella amazonensis SB2B

Annotation: cytochrome c-type biogenesis protein CcmH (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 106 to 127 (22 residues), see Phobius details TIGR03147: cytochrome c nitrite reductase, accessory protein NrfF" amino acids 7 to 129 (123 residues), 177.7 bits, see alignment E=3.6e-57 PF03918: CcmH" amino acids 11 to 152 (142 residues), 184.2 bits, see alignment E=3.8e-59

Best Hits

KEGG orthology group: K02200, cytochrome c-type biogenesis protein CcmH (inferred from 100% identity to saz:Sama_0250)

Predicted SEED Role

"Cytochrome c heme lyase subunit CcmL" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S255 at UniProt or InterPro

Protein Sequence (167 amino acids)

>Sama_0250 cytochrome c-type biogenesis protein CcmH (RefSeq) (Shewanella amazonensis SB2B)
MKPLNLLLAMVLFCISTLTFATPVDTYEFKSADNQKRALSLAHELRCPQCQNQNLIDSNS
PVARDLRLEVYKMVDEGKSDDQIIEFMTTRYGDFVLYKPRVEGRTYILWLGPVALLLIGL
MVVILFIRKQRSQTADAADLTPEQQAELDALLKGSQPEADNGKGKKS