Protein Info for Sama_0056 in Shewanella amazonensis SB2B

Annotation: Rrf2 family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 151 TIGR00738: Rrf2 family protein" amino acids 1 to 130 (130 residues), 100.8 bits, see alignment E=2.8e-33 PF02082: Rrf2" amino acids 3 to 131 (129 residues), 115.2 bits, see alignment E=1.2e-37

Best Hits

Swiss-Prot: 51% identical to NSRR_SHIB3: HTH-type transcriptional repressor NsrR (nsrR) from Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)

KEGG orthology group: K13771, Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor (inferred from 100% identity to saz:Sama_0056)

Predicted SEED Role

"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S1L2 at UniProt or InterPro

Protein Sequence (151 amino acids)

>Sama_0056 Rrf2 family protein (RefSeq) (Shewanella amazonensis SB2B)
MQLTRYTDFGIRTLMYMAVQPERTALFRIAEITEVFDLSPNHVSKIIHHLGKAGYLQTVR
GKAGGFRLAKPAAEINLGALVRELEHSLAPINCSKPVCRLLPACQLKGVLANAVQAYLAV
LDQYQLADIVTNRDELLALLPDSTISILQLG