Protein Info for Shew_3597 in Shewanella loihica PV-4

Annotation: inner membrane protein YjeH (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 64 (23 residues), see Phobius details amino acids 89 to 111 (23 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 148 to 167 (20 residues), see Phobius details amino acids 185 to 207 (23 residues), see Phobius details amino acids 220 to 243 (24 residues), see Phobius details amino acids 263 to 291 (29 residues), see Phobius details amino acids 311 to 334 (24 residues), see Phobius details amino acids 340 to 360 (21 residues), see Phobius details amino acids 367 to 384 (18 residues), see Phobius details amino acids 389 to 405 (17 residues), see Phobius details PF13520: AA_permease_2" amino acids 8 to 385 (378 residues), 128.8 bits, see alignment E=2.8e-41 PF00324: AA_permease" amino acids 21 to 392 (372 residues), 89.9 bits, see alignment E=1.6e-29

Best Hits

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 100% identity to slo:Shew_3597)

Predicted SEED Role

"putative transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QJ15 at UniProt or InterPro

Protein Sequence (419 amino acids)

>Shew_3597 inner membrane protein YjeH (RefSeq) (Shewanella loihica PV-4)
MEHNHGTIGRWQGAGLMATTLLGTGVFILPEMTIATAGSGALLAWILLTLAIIPVTLVFA
RLAGVFPHAAGPAYFVEKAFGRTAGRTTGLIFLLVVPIGTPAAILMTFQFINALVPLVGW
QQLMTELALLLLLLALNLKGIQVSAKLQFALTLAIVSVVVILFGAGGAKLGDLELAAPQA
GSDMGLVMAAAGIAFWSFLGIEAMTHLANDFKRPDKDMLPAMIIGTILVGLVYVTCTLLL
LFVPKGEGLAMVTAFDHLLGGYGAQVIGILGIAGGLSTVNVYTASVARLIWSFSREGVLP
RYFDKLNQHRVPVRALVAVLLTMATVICLTYLLGQELEHLIAWTNGVFVLIYLVSMLAAA
RLLSKRYLPLVIMGVAFCLAMAVALGANMLYALMLVSVLAPLLWWQKTHLVRKQTCRAS